Academic Journal
Bafilomycin A1 and intracellular multiplication of Legionella pneumophila
| العنوان: | Bafilomycin A1 and intracellular multiplication of Legionella pneumophila |
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| المؤلفون: | Cattani, L, Goldoni, P, Pastoris, M C, Sinibaldi, L, Orsi, N |
| المصدر: | Antimicrobial Agents and Chemotherapy ; volume 41, issue 1, page 212-214 ; ISSN 0066-4804 1098-6596 |
| بيانات النشر: | American Society for Microbiology |
| سنة النشر: | 1997 |
| الوصف: | Multiplication of Legionella pneumophila in HeLa cells was found to be inhibited by noncytotoxic concentrations of bafilomycin A1, with blockage of bacterial growth at a concentration 15.6 nM. The inhibiting action was evident only when the antibiotic was present during the initial phase of intracellular multiplication, i.e., during the formation of the phagosome, whereas the addition of the drug did not affect microorganisms already actively multiplying within the phagosome. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1128/aac.41.1.212 |
| DOI: | 10.1128/AAC.41.1.212 |
| الاتاحة: | http://dx.doi.org/10.1128/aac.41.1.212 https://journals.asm.org/doi/pdf/10.1128/AAC.41.1.212 |
| Rights: | https://journals.asm.org/non-commercial-tdm-license |
| رقم الانضمام: | edsbas.BF91FCF9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1128/aac.41.1.212 |
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