Academic Journal
MicroRNAs and hematopoietic differentiation
| العنوان: | MicroRNAs and hematopoietic differentiation |
|---|---|
| المؤلفون: | Fatica A., Rosa A., Fazi F., Ballarino M., Morlando M., De Angelis F. G., Caffarelli E., Nervi C., Bozzoni I. |
| المساهمون: | Fatica, A., Rosa, A., Fazi, F., Ballarino, M., Morlando, M., De Angelis, F. G., Caffarelli, E., Nervi, C., Bozzoni, I. |
| سنة النشر: | 2006 |
| المجموعة: | IRIS Università degli Studi di Perugia |
| مصطلحات موضوعية: | Cell Differentiation, Gene Expression Regulation, Developmental, Hematopoiesi, Human, Leukemia, MicroRNA, Models, Biological, RNA, Neoplasm, Transcription Factors |
| الوصف: | The discovery of microRNAs (miRNAs) and of their mechanism of action has provided some very new clues on how gene expression is regulated. These studies established new concepts on how posttranscriptional control can fine-tune gene expression during differentiation and allowed the identification of new regulatory circuitries as well as factors involved therein. Because of the wealth of information available about the transcriptional and cellular networks involved in hematopoietic differentiation, the hematopoietic system is ideal for studying cell lineage specification. An interesting interplay between miRNAs and lineage-specific transcriptional factors has been found, and this can help us to understand how terminal differentiation is accomplished. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/17381298; info:eu-repo/semantics/altIdentifier/wos/WOS:000245962800027; volume:71; issue:0; firstpage:205; lastpage:210; numberofpages:6; journal:COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY; http://hdl.handle.net/11391/1456210; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-34250654985; http://symposium.cshlp.org/content/71/205.full.pdf+html |
| DOI: | 10.1101/sqb.2006.71.014 |
| الاتاحة: | http://hdl.handle.net/11391/1456210 https://doi.org/10.1101/sqb.2006.71.014 http://symposium.cshlp.org/content/71/205.full.pdf+html |
| رقم الانضمام: | edsbas.BF3F3504 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1101/sqb.2006.71.014 |
|---|