Academic Journal
Impact of gender on the utilization of cardiac implantable devices and outcome: results from the German DEVICE registry
| العنوان: | Impact of gender on the utilization of cardiac implantable devices and outcome: results from the German DEVICE registry |
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| المؤلفون: | Popescu, S S, Gasperetti, A, Brachmann, J, Eckardt, L, Kuck, K H, Willems, S, Hochadel, M, Senges, J, Tilz, R R |
| المصدر: | Europace ; volume 25, issue Supplement_1 ; ISSN 1099-5129 1532-2092 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Physiology (medical), Cardiology and Cardiovascular Medicine |
| الوصف: | Funding Acknowledgements Type of funding sources: None. Background Implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy (CRT) are widely used in patients with life-threatening cardiac arrhythmias or systolic heart failure. Real world data regarding gender impact on ICD and CRT implantation and outcome is scarce. Purpose To investigate the impact of gender-specific differences on cardiac devices implantation and outcomes. Methods The German DEVICE registry is a nationwide prospective multicentre database of ICD and CRT devices implantation. A total of 5451 patients were prospectively enrolled in 44 centres between March 2007 and February 2014 and were monitored for a median of 17 months. Results A minority of patients in this registry was female 1050 (19.3%; mean age 64.4 ± 14.6 years; median BMI 27.2) while men represented 80.7% (mean age 65.5 ± 12.4 years; median BMI 26.8). Female patients were less likely to have a LVEF <35% (70.6% vs. 77.7%; p<0.0001) and more likely to have a LVEF >55% (13.3% vs. 6.6%; p<0.0001). Moreover, women were less likely to have coronary artery disease (42.3% vs. 64.7%; p<0.0001), history of myocardial infarction, percutaneous coronary intervention, and coronary artery bypass graft (p<0.0001 for all). The rate of CRTs was significantly higher in women than in men (33.4% vs. 28.7%; p=0.0036). In terms of secondary prevention implantations, women were more likely to have history of ventricular fibrillation (VF; 50.7% vs. 37.2%; p<0.0001) but less likely to have history of ventricular tachycardia (VT; 34.5% vs. 47.5%; p<0.0001). The rates of major periprocedural complications and in-hospital complications were higher in women (3.3% vs. 1.7%; p=0.002 and 5.6% vs. 3.7%; p=0.0208). The Kaplan-Meier estimated 1-year all-cause mortality was 5.4% for women and 7.4% for men, while the overall mortality during follow-up was 10% for women and 14% for men (p=0.0004), with no gender differences in ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1093/europace/euad122.428 |
| الاتاحة: | http://dx.doi.org/10.1093/europace/euad122.428 https://academic.oup.com/europace/article-pdf/25/Supplement_1/euad122.428/50428870/euad122.428.pdf |
| Rights: | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| رقم الانضمام: | edsbas.BEE2526B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/europace/euad122.428 |
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