التفاصيل البيبلوغرافية
| العنوان: |
Child Neurodevelopment After Multidomain Interventions From Preconception Through Early Childhood |
| المؤلفون: |
Upadhyay, Ravi Prakash, Taneja, Sunita, Chowdhury, Ranadip, Dhabhai, Neeta, Sapra, Savita, Mazumder, Sarmila, Sharma, Sitanshi, Tomlinson, Mark, Dua, Tarun, Chellani, Harish, Dewan, Rupali, Mittal, Pratima, Bhan, M. K., Bhandari, Nita, Shekhawat, R.S., Siraj, S, Nagpal, Sugandhi, Abbasi, Farah, Chaudhary, Heena, Sharma, Karishma, Rafiqui, Farhana, Bhatia, Kiran, Kaur, Jasmine, Shekhar, Medha, Kate, Anita, Aggarwal, Gunjan, Ghosh, Runa, Kishore, K.V. Ravi, Mehra, Navneet, Arya, Nikita, Chaudhary, Ritu, Tamaria, Anuradha, Kumar, Tivendra, C, Sowmya Karantha, Modi, Purnima, Kaur, Neelam, Tyagi, Neha, Mehto, Geeta, Khatun, Afifa, Sayeed, Ahmed, Singh, Aparna, Ansari, Gulafshan, Kaur, Ramanjeet, Gupta, Manisha, Pant, G. C., Dutta, Ankita, More, Deepak, Kumar, Mukesh, Kuruvilla, Sonia, Chandra, Anjali, Debata, Pradeep, Yadav, Anita, Jain, Abhinav, Sachdev, Rahul, Bansal, Omprakash, Agarwal, Raghav |
| المصدر: |
JAMA, 331(1), (2024-01-02) |
| بيانات النشر: |
Zenodo |
| سنة النشر: |
2024 |
| المجموعة: |
Zenodo |
| الوصف: |
Importance Multidomain interventions in pregnancy and early childhood have improved child neurodevelopment, but little is known about the effects of additional preconception interventions. Objective To evaluate the effect of a multifaceted approach including health; nutrition; water, sanitation, and hygiene (WASH); and psychosocial support interventions delivered during the preconception period and/or during pregnancy and early childhood on child neurodevelopment. Design, Setting, and Participants In this randomized trial involving low- and middle-income neighborhoods in Delhi, India, 13 500 participants were assigned to preconception interventions or routine care for the primary outcome of preterm births and childhood growth. Participants who became pregnant were randomized to pregnancy and early childhood interventions or routine care. Neurodevelopmental assessments, the trial's secondary outcome reported herein, were conducted in a subsample of children at age 24 months, including 509 with preconception, pregnancy, and early childhood interventions; 473 with preconception interventions alone; 380 with pregnancy and early childhood interventions alone; and 350 with routine care. This study was conducted from November 1, 2020, through February 25, 2022. Interventions Health, nutrition, psychosocial care and support, and WASH interventions delivered during preconception, pregnancy, and early childhood periods. Main Outcomes and Measures Cognitive, motor, language, and socioemotional performance at age 24 months, assessed using the Bayley Scales of Infant and Toddler Development 3 tool. Results The mean age of participants at enrollment was 23.8 years (SD, 3.0 years). Compared with the controls at age 24 months, children in the preconception intervention groups had higher cognitive scores (mean difference [MD], 1.16; 98.3% CI, 0.18-2.13) but had similar language, motor, and socioemotional scores as controls. Those receiving pregnancy and early childhood interventions had higher cognitive (MD, 1.48; 98.3% CI, ... |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| Relation: |
https://doi.org/10.1001/jama.2023.23727; https://zenodo.org/communities/gates-foundation; https://doi.org/10.5281/zenodo.14045121; https://doi.org/10.5281/zenodo.14045122; oai:zenodo.org:14045122 |
| DOI: |
10.5281/zenodo.14045122 |
| الاتاحة: |
https://doi.org/10.5281/zenodo.14045122 |
| Rights: |
info:eu-repo/semantics/openAccess ; Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcode |
| رقم الانضمام: |
edsbas.BE37942C |
| قاعدة البيانات: |
BASE |