Academic Journal

Development Of Functional Material Scaffolds for Sensing Applications

التفاصيل البيبلوغرافية
العنوان: Development Of Functional Material Scaffolds for Sensing Applications
المؤلفون: Madhumati Ramanathan
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: https://etd.auburn.edu/bitstream/handle/10415/2031/Final%20Dissertation-1.PDF%3Bjsessionid%3D8442995436FA918DD51245DAC330B030?sequence%3D1.
سنة النشر: 2010
المجموعة: CiteSeerX
مصطلحات موضوعية: Array biosensor, titanium dioxide, silica, immobilization, lysozyme, florisil
الوصف: ii Developments in the field of chemical and biological sensors call for sensitive and selective sensing surfaces to provide consistent information about target analytes. Since such sensors are mostly operating in complex multi-component environments, their interaction with interferent can have deleterious effects on their activity. Thus, stable sensing surfaces form the most critical aspect of a biosensor design and their development requires reliable surface morphology and chemistry for allocation of chemical and bio-recognition elements. Studies in this dissertation were aimed at developing modified titanium dioxide nanoparticles using techniques such as silanization and cross-linking to act as scaffolds for stable immobilization of proteins via direct covalent bonding or encapsulation in silica particles during its bio-inspired lysozyme mediation. Spatially defined presence of protein-reporter agents, on transparent titania nanoparticles coated on glass slides, enabled the development of fluorimetric array biosensors for simultaneous detection of
نوع الوثيقة: text
اللغة: English
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1028.1875
الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1028.1875
Rights: Metadata may be used without restrictions as long as the oai identifier remains attached to it.
رقم الانضمام: edsbas.BE22451E
قاعدة البيانات: BASE