التفاصيل البيبلوغرافية
| العنوان: |
Self-Assembled Homopolymeric Spherulites from Small Molecules in Solution |
| المؤلفون: |
Qiantao Song, Yi Li, Zhicheng Jin, Hai Liu, Matthew N. Creyer, Wonjun Yim, Yanping Huang, Xiaobing Hu, Tengyu He, Yajuan Li, Shana O. Kelley, Lingyan Shi, Jiajing Zhou, Jesse V. Jokerst |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
Biophysics, Biochemistry, Cell Biology, Genetics, Pharmacology, Biotechnology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, via disulfide bonds, underwent chain elongation, traceable drug carriers, simple molecule benzene, room temperature via, requires complex polymers, exhibited robust structure, efficient cellular uptake, e ., dimethylformamide, designing versatile superstructures, complicated biological system, uniform supramolecular nanoparticles, solution polymeric spherulites, assembled homopolymeric spherulites, system provides, luminescent spherulites, form spherulites, unique formation, typically formed, triggered emission, spherulitic growth |
| الوصف: |
Polymeric spherulites are typically formed by melt crystallization: spherulitic growth in solution is rare and requires complex polymers and dilute solutions. Here, we report the mild and unique formation of luminescent spherulites at room temperature via the simple molecule benzene-1,4-dithiol (BDT). Specifically, BDT polymerized into oligomers (PBDT) via disulfide bonds and assembled into uniform supramolecular nanoparticles in aqueous buffer; these nanoparticles were then dissolved back into PBDT in a good solvent (i.e., dimethylformamide) and underwent chain elongation to form spherulites (rPBDT) in 10 min. The spherulite geometry was modulated by changing the PBDT concentration and reaction time. Due to the step-growth polymerization and reorganization of PBDT, these spherulites not only exhibited robust structure but also showed broad clusterization-triggered emission. The biocompatibility and efficient cellular uptake of the spherulites further underscore their value as traceable drug carriers. This system provides a new pathway for designing versatile superstructures with value for hierarchical assembly of small molecules into a complicated biological system. |
| نوع الوثيقة: |
dataset |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/media/Self-Assembled_Homopolymeric_Spherulites_from_Small_Molecules_in_Solution/24495811 |
| DOI: |
10.1021/jacs.3c08356.s002 |
| الاتاحة: |
https://doi.org/10.1021/jacs.3c08356.s002
https://figshare.com/articles/media/Self-Assembled_Homopolymeric_Spherulites_from_Small_Molecules_in_Solution/24495811 |
| Rights: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.BDDA05CE |
| قاعدة البيانات: |
BASE |