Academic Journal
Tear Lysozyme in Sjögren´s syndrome, Meibomian gland dysfunction, and non-dry-eye ; Lisozima lacrimal na síndrome de Sjögren, disfunção da glândula meibomiana e olho não seco
| العنوان: | Tear Lysozyme in Sjögren´s syndrome, Meibomian gland dysfunction, and non-dry-eye ; Lisozima lacrimal na síndrome de Sjögren, disfunção da glândula meibomiana e olho não seco |
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| المؤلفون: | Berra, Martín, Galperin, Gustavo, Berra, Federico Nicolás, Márquez, María Isabel, Mandaradoni, Mariana, Tau, Julia, Berra, Alejandro |
| بيانات النشر: | Conselho Brasileiro de Oftalmologia |
| المجموعة: | CONICET Digital (Consejo Nacional de Investigaciones Científicas y Técnicas) |
| مصطلحات موضوعية: | DRY EYE, BIOMARKER, TEAR, LYSOZYME, https://purl.org/becyt/ford/3.3, https://purl.org/becyt/ford/3 |
| الوصف: | Purpose: To evaluate the concentration of tear lysozyme in individuals with Sjogren´s syndrome, meibomian gland dysfunction, and non-dry-eye disease. Methods: Ninety subjects were recruited for this study, including 30 with Sjogren´s syndrome, 30 with meibomian gland dysfunction, and 30 with non-dry-eye disease. All subjects were referred to participate in the study based on a “dry eye” investigation. They underwent a complete ocular surface ophthalmic examination encompassing ocular surface disease index, biomicroscopy, tear break-up time, Schirmer test type I, conjunctival vital staining with fluorescein and lissamine green, tear lysozyme concentration, and impression cytology. Results: Clinical tests yielded the following results: ocular surface disease index Sjogren´s syndrome: 64.5 ± 22.6 meibomian gland dysfunction: 43.5 ± 21.4, non-dry-eye disease: 6.7 ± 4.3 (p=0.02 between groups); Schirmer I test (mm/5 min): Sjogren´s syndrome: 4.95 ± 2.25, meibomian gland dysfunction: 13.28 ± 1.53, non-dry-eye disease 13.70 ± 1.39 (p<0.01 Sjogren´s syndrome vs. non-dry-eye disease and p<0.01 meibomian gland dysfunction vs. non-dry-eye disease); tear break-up time (seconds): Sjogren´s syndrome: 3.97 ± 1.47, meibomian gland dysfunction: 3.95 ± 0.86, non-dry-eye disease: 7.25 ± 1.90 (p<0.01 Sjogren´s syndrome vs. non-dry-eye disease and p<0.01 meibomian gland dysfunction vs. non-dry-eye disease); Lissamine green score: Sjogren´s syndrome-dry-eye: 6.18 ± 2.14, meibomian gland dysfunction-dry-eye: 5.27 ± 1.27, non-dry-eye disease: 1.52 ± 0.97 (p<0.01 Sjogren´s syndrome vs. non-dry-eye disease and p<0.01 meibomian gland dysfunction vs. non-dry-eye disease); impression cytology score: Sjogren´s syndrome: 1.88 ± 0.92, meibomian gland dysfunction: 1.67 ± 0.56, non-dry-eye: 0.45 ± 0.44 (p<0.01 Sjogren´s syndrome vs. non-dry-eye disease and p<0.01 meibomian gland dysfunction vs. non-dry-eye disease) and; tear lysozyme concentration (µg/mL): Sjogren´s syndrome: 751.25 ± 244.73, meibomian gland dysfunction: ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0004-2749 1678-2925 |
| Relation: | info:eu-repo/semantics/altIdentifier/url/http://aboonline.org.br/details/6162/en-US/tear-lysozyme-in-sjogren%C2%B4s-syndrome--meibomian-gland-dysfunction--and-non-dry-eye; info:eu-repo/semantics/altIdentifier/url/https://www.scielo.br/j/abo/a/dDHLMnL7tQDHVfQ57QKtKwP/?lang=en; http://hdl.handle.net/11336/156668; Berra, Martín; Galperin, Gustavo; Berra, Federico Nicolás; Márquez, María Isabel; Mandaradoni, Mariana; et al.; Tear Lysozyme in Sjögren´s syndrome, Meibomian gland dysfunction, and non-dry-eye; Conselho Brasileiro de Oftalmologia; Arquivos Brasileiros de Oftalmologia; 85; 2; 11-2020; 103-108; CONICET Digital; CONICET |
| الاتاحة: | http://hdl.handle.net/11336/156668 |
| Rights: | info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by-nc/2.5/ar/ |
| رقم الانضمام: | edsbas.BC130F3F |
| قاعدة البيانات: | BASE |
| تدمد: | 00042749 16782925 |
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