Academic Journal
The growing role of precision medicine for the treatment of autoimmune diseases; results of a systematic review of literature and Experts’ Consensus
| العنوان: | The growing role of precision medicine for the treatment of autoimmune diseases; results of a systematic review of literature and Experts’ Consensus |
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| المؤلفون: | Giacomelli R., Afeltra A., Bartoloni E., Berardicurti O., Bombardieri M., Bortoluzzi A., Carubbi F., Caso F., Cervera R., Ciccia F., Cipriani P., Coloma-Bazan E., Conti F., Costa L., D'Angelo S., Distler O., Feist E., Foulquier N., Gabini M., Gerber V., Gerli R., Grembiale R. D., Guggino G., Hoxha A., Iagnocco A., Jordan S., Kahaleh B., Lauper K., Liakouli V., Lubrano DI SCORPANIELLO E., Margiotta D., Naty S., Navarini L., Perosa F., Perricone C., Perricone R., Prete M., Pers J. -O., Pitzalis C., Priori R., Rivellese F., Ruffatti A., Ruscitti P., Scarpa R., Shoenfeld Y., Triolo G., Tzioufas A. |
| المساهمون: | Giacomelli, R., Afeltra, A., Bartoloni, E., Berardicurti, O., Bombardieri, M., Bortoluzzi, A., Carubbi, F., Caso, F., Cervera, R., Ciccia, F., Cipriani, P., Coloma-Bazan, E., Conti, F., Costa, L., D'Angelo, S., Distler, O., Feist, E., Foulquier, N., Gabini, M., Gerber, V., Gerli, R., Grembiale, R. D., Guggino, G., Hoxha, A., Iagnocco, A., Jordan, S., Kahaleh, B., Lauper, K., Liakouli, V., Lubrano DI SCORPANIELLO, E., Margiotta, D., Naty, S., Navarini, L., Perosa, F., Perricone, C., Perricone, R., Prete, M., Pers, J. -O., Pitzalis, C., Priori, R., Rivellese, F., Ruffatti, A., Ruscitti, P., Scarpa, R., Shoenfeld, Y., Triolo, G., Tzioufas, A. |
| سنة النشر: | 2021 |
| المجموعة: | Università degli Studi del Molise: IRIS |
| مصطلحات موضوعية: | antiphospholipid syndrome, Precision medicine, primary Sjogren's syndrome, rheumatoid arthriti, spondyloarthritide, systemic lupus erythematosu, systemic sclerosis |
| الوصف: | Autoimmune diseases (AIDs) share similar serological, clinical, and radiological findings, but, behind these common features, there are different pathogenic mechanisms, immune cells dysfunctions, and targeted organs. In this context, multiple lines of evidence suggest the application of precision medicine principles to AIDs to reduce the treatment failure. Precision medicine refers to the tailoring of therapeutic strategies to the individual characteristics of each patient, thus it could be a new approach for management of AIDS which considers individual variability in genes, environmental exposure, and lifestyle. Precision medicine would also assist physicians in choosing the right treatment, the best timing of administration, consequently trying to maximize drug efficacy, and, possibly, reducing adverse events. In this work, the growing body of evidence is summarized regarding the predictive factors for drug response in patients with AIDs, applying the precision medicine principles to provide high-quality evidence for therapeutic opportunities in improving the management of these patients. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/wos/WOS:000613277000011; firstpage:102738; journal:AUTOIMMUNITY REVIEWS; http://hdl.handle.net/11695/96311; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85099369813 |
| DOI: | 10.1016/j.autrev.2020.102738 |
| الاتاحة: | http://hdl.handle.net/11695/96311 https://doi.org/10.1016/j.autrev.2020.102738 |
| رقم الانضمام: | edsbas.BBE5CA48 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.autrev.2020.102738 |
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