Academic Journal
Zika Virus Disease in Children in Colombia, August 2015 to May 2016
| العنوان: | Zika Virus Disease in Children in Colombia, August 2015 to May 2016 |
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| المؤلفون: | Tolosa, Natalia, Tinker, Sarah C., Pacheco, Oscar, Valencia, Diana, Botero, Daniela Salas, Tong, Van T., Mercado, Marcela, Gilboa, Suzanne M., Gonzalez, Maritza, Nelson, Christina A., Pardo, Lissethe, Rao, Carol Y., Rico, Angélica, Moore, Meredith, Parra, Edgar, Honein, Margaret A., Ospina Martínez, Martha L. |
| المصدر: | Paediatric and Perinatal Epidemiology ; volume 31, issue 6, page 537-545 ; ISSN 0269-5022 1365-3016 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2017 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Background Children are considered a potentially vulnerable population for Zika virus infection. However, data on paediatric Zika virus infection are sparse. Methods We analysed data from Colombia's national surveillance system during the 2015–2016 Zika virus outbreak on patients meeting the clinical case definition of Zika virus disease ( ZVD ) among children aged 1 month to 18 years to estimate incidence by demographic characteristics and characterize the occurrence of selected complications. Results Between August 14, 2015, and May 28, 2016, there were 18 576 reported cases of postnatal ZVD among children aged 1 month to 18 years. Laboratory testing was prioritized for high‐risk patients (infants, pregnant women, adults aged ≥65 years, and persons with serious co‐morbidities); among 1655 that were tested by real‐time reverse transcriptase polymerase chain reaction, 1207 (72.9%) were positive. The cumulative incidence of reported ZVD was 114.4 per 100 000. The incidence differed by sex, depending on age group; the largest difference was observed for 15–18 year olds, with females having a higher incidence than males (cumulative incidence ratio 2.5, 95% confidence interval 2.3, 2.7). At the time of report to the surveillance system, 631 patients (3.4%) were hospitalised and 96 (0.5%) had a report of an accompanying neurological diagnosis, including Guillain‐Barré syndrome in 40 patients. Conclusions Only a small proportion of reported paediatric ZVD cases in Colombia were hospitalized or had reported neurological conditions following ZVD . However, the potential for some serious outcomes demonstrates the importance of preventing Zika virus infection in children. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1111/ppe.12391 |
| الاتاحة: | http://dx.doi.org/10.1111/ppe.12391 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fppe.12391 https://onlinelibrary.wiley.com/doi/pdf/10.1111/ppe.12391 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.BB597C7A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/ppe.12391 |
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