الوصف: |
Bo-Hao Zheng,1,2,* Zhi-Xian He,3,* Juan Zhang,4,* Jing-Jing Ma,5,* Hong-Wei Zhang,1,2 Wei Zhu,1,2 Zhi-Min Shao,6 Xiao-Jian Ni1,2 1Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of China; 2Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of China; 3Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, 226001, People’s Republic of China; 4Liver Cancer Institute, Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University, Shanghai, 200032, People’s Republic of China; 5State Key Laboratory of Reproductive Medicine, Department of Breast Surgery, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, 210004, People’s Republic of China; 6Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Cancer Center and Cancer Institute, Fudan University, Shanghai, 200032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiao-Jian NiDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of ChinaTel/Fax +86-21-64041990Email ni.xiaojian@zs-hospital.sh.cnZhi-Min ShaoDepartment of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Cancer Center and Cancer Institute, Fudan University, Shanghai, 200032, People’s Republic of ChinaTel/Fax +86-21-64175590Email shaozhimingfd@163.comBackground: Triple-negative breast cancers (TNBC), comprising about 20% of breast cancers, have a poor prognosis. Currently, there is no effective target therapy for TNBC. LncRNA TUSC7 has been identified as a tumor suppressor in osteosarcoma and colorectal cancer. In this study, we investigated the clinical significance and the biological function of TUSC7 in breast cancer.Methods: We retrospectively evaluated the expression level and clinical significance of TUSC7 in 90 paired breast cancer tissues and ... |