Academic Journal
Integration of sub-classification strategies in RCTs evaluating manual therapy treatment and exercise therapy for non-specific chronic low back pain (NSCLBP): a systematic review
| العنوان: | Integration of sub-classification strategies in RCTs evaluating manual therapy treatment and exercise therapy for non-specific chronic low back pain (NSCLBP): a systematic review |
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| المؤلفون: | Fersum, Kjartan Vibe, Dankaerts, Wim, O'Sullivan, Peter Bruce, Maes, Jonas, Skouen, Jan Sture, Bjordal, Jan Magnus, Kvåle, Alice |
| بيانات النشر: | BMJ Publishing Group Ltd |
| سنة النشر: | 2009 |
| المجموعة: | HighWire Press (Stanford University) |
| مصطلحات موضوعية: | Review |
| الوصف: | Background: There is lack of evidence for specific treatment interventions for patients with non-specific chronic low back pain (NSCLBP) despite the substantial amount of Randomised Controlled clinical Trials (RCTs) evaluating treatment outcome for this disorder. Hypothesis: It has been hypothesised that this vacuum of evidence is caused by the lack of sub-classifying the heterogeneous population of patients with CLBP for outcome research. Study design: A systematic review (SR). Methods: A systematic review with a meta-analysis (MA) was undertaken to determine the integration of sub-classification strategies with matched interventions in RCTs evaluating manual therapy treatment and exercise therapy for NSCLBP. A structured search for relevant studies in Embase, Cinahl, Medline, PEDro and the Cochrane Trials Register database, followed by hand searching all relevant studies in English up till December 2008. Results: Only 5 out of 68 studies (7.4%) sub-classified patients beyond applying general in- and exclusion criteria. In the few studies where classification and matched interventions have been utilised, our meta-analysis showed a statistical difference in favour of the classification based intervention for reductions in pain (p= 0.004) and disability (p= 0.0005), both for short and long-term reduction in pain (p= 0.001). Effect sizes ranged from moderate (0.43) short term, to minimal (0.14) for long-term. Conclusion: A better integration of sub-classification strategies in NSCLBP outcome research is needed. We propose the development of explicit recommendations for the use of sub-classification strategies and evaluation of targeted interventions in future research evaluating NSCLBP. |
| نوع الوثيقة: | text |
| وصف الملف: | text/html |
| اللغة: | English |
| Relation: | http://bjsm.bmj.com/cgi/content/short/bjsm.2009.063289v1; http://dx.doi.org/10.1136/bjsm.2009.063289 |
| DOI: | 10.1136/bjsm.2009.063289 |
| الاتاحة: | http://bjsm.bmj.com/cgi/content/short/bjsm.2009.063289v1 https://doi.org/10.1136/bjsm.2009.063289 |
| Rights: | Copyright (C) 2009, British Association of Sport and Excercise Medicine |
| رقم الانضمام: | edsbas.BA9BDEB7 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/bjsm.2009.063289 |
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