التفاصيل البيبلوغرافية
| العنوان: |
Survival outcomes following modern multidisciplinary management of oral squamous cell carcinoma in Australia |
| المؤلفون: |
Liu, Timothy P. J., Fisher, Bradley M., Chua, Benjamin, Clark, Jonathan R., Low, Tsu-Hui (Hubert), Batstone, Martin D. |
| بيانات النشر: |
Elsevier |
| سنة النشر: |
2020 |
| المجموعة: |
The University of Queensland: UQ eSpace |
| مصطلحات موضوعية: |
Pathology and Forensic Medicine, Surgery, Oral Surgery, Dentistry (miscellaneous), Radiology Nuclear Medicine and imaging, 2734 Pathology and Forensic Medicine, 2741 Radiology Nuclear Medicine and imaging, 2746 Surgery, 3501 Dentistry (miscellaneous), 3504 Oral Surgery |
| الوصف: |
Oral squamous cell carcinoma (SCC) has been traditionally described as a highly lethal disease. This study aims to provide updated multi-institutional data on the survival of patients with oral SCC in Australia.Retrospective survival analysis was performed between 2008 and 2016. All new patients with oral SCC treated with curative intent were recruited from 2 high-volume Australian head and neck oncology centers. Outcomes were measured in overall survival (OS), disease-specific survival (DSS), disease-free survival, and salvage rates for recurrences.Survival analysis included 771 patients with oral SCC. Five-year OS and DSS were 66.1% and 79.7%, respectively. Stage I and II oral SCC had significantly better survival than higher stages. Five-year OS and DSS for patients with stage I SCC were 79.7% and 93.4%, respectively, and for patients with stage IVB they were 37.9% and 54.3%, respectively. Two hundred forty-nine patients had disease recurrence (32.3%), with 66 patients (26.5% remaining disease free post salvage treatment.Survival outcomes for oral SCC among Australian patients have improved, possibly due to advances in multidisciplinary care. Early detection of oral SCC leads to highly favorable prognosis; there is therefore an opportunity for routine oral cancer screening to be performed by community health practitioners with the aim of improving survival from oral SCC. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| تدمد: |
2212-4403 |
| Relation: |
orcid:0000-0002-2403-813X; orcid:0000-0002-9058-9976 |
| الاتاحة: |
https://espace.library.uq.edu.au/view/UQ:4efccc1 |
| رقم الانضمام: |
edsbas.BA18B596 |
| قاعدة البيانات: |
BASE |