التفاصيل البيبلوغرافية
| العنوان: |
Melanopsin photoreception differentially modulates rod-mediated and cone-mediated human temporal vision |
| المؤلفون: |
Uprety, Samir, Adhikari, Prakash, Feigl, Beatrix, Zele, Andrew J. |
| المصدر: |
iScience |
| بيانات النشر: |
Elsevier Inc. |
| سنة النشر: |
2022 |
| المجموعة: |
Queensland University of Technology: QUT ePrints |
| مصطلحات موضوعية: |
Applied sensory psychophysics, Cellular neuroscience, Sensory neuroscience |
| الوصف: |
To evaluate the nature of interactions between visual pathways transmitting the slower melanopsin and faster rod and cone signals, we implement a temporal phase summation paradigm in human observers using photoreceptor-directed stimuli. We show that melanopsin stimulation interacts with and alters both rod-mediated and cone-mediated vision regardless of whether it is perceptually visible or not. Melanopsin-rod interactions result in either inhibitory or facilitatory summation depending on the temporal frequency and photoreceptor pathway contrast sensitivity. Moreover, by isolating rod vision, we reveal a bipartite intensity response property of the rod pathway in photopic lighting that extends its operational range at lower frequencies to beyond its classic saturation limits but at the expense of attenuating sensitivity at higher frequencies. In comparison, melanopsin-cone interactions always lead to facilitation. These interactions can be described by linear or probability summations and potentially involve multiple intraretinal and visual cortical pathways to set human visual contrast sensitivity. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
unknown |
| Relation: |
https://eprints.qut.edu.au/233533/1/1_s2.0_S2589004222008008_main.pdf; Uprety, Samir, Adhikari, Prakash, Feigl, Beatrix, & Zele, Andrew J. (2022) Melanopsin photoreception differentially modulates rod-mediated and cone-mediated human temporal vision. iScience, 25(7), Article number: 104529.; http://purl.org/au-research/grants/arc/FT180100458; https://eprints.qut.edu.au/233533/; Centre for Vision and Eye Research; Faculty of Health; School of Biomedical Sciences; School of Optometry & Vision Science |
| الاتاحة: |
https://eprints.qut.edu.au/233533/ |
| Rights: |
free_to_read ; http://creativecommons.org/licenses/by/2.5/ ; © 2022 The Author(s) ; This work is covered by copyright. Unless the document is being made available under a Creative Commons Licence, you must assume that re-use is limited to personal use and that permission from the copyright owner must be obtained for all other uses. If the document is available under a Creative Commons License (or other specified license) then refer to the Licence for details of permitted re-use. It is a condition of access that users recognise and abide by the legal requirements associated with these rights. If you believe that this work infringes copyright please provide details by email to qut.copyright@qut.edu.au |
| رقم الانضمام: |
edsbas.B9A07666 |
| قاعدة البيانات: |
BASE |