Academic Journal
Risk factors for bacteremia and Its clinical impact on complicated community-acquired urinary tract infection
| العنوان: | Risk factors for bacteremia and Its clinical impact on complicated community-acquired urinary tract infection |
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| المؤلفون: | Madrazo, Manuel, López Cruz, Ian, Piles, Laura, Artero, Silvia, Alberola, Juan, Aguilera, Juan Alberto, Eiros Bouza, José María, Artero, Arturo |
| بيانات النشر: | MDPI |
| سنة النشر: | 2023 |
| المجموعة: | UVaDOC - Repositorio Documental de la Universidad de Valladolid |
| مصطلحات موضوعية: | Risk factors, Bacteremia, Urinary tract infections, Vías urinarias - Infecciones, Urinario, Aparato - Infecciones, Urology, Microbiology, Public health, 3213.16 Urología, 32 Ciencias Médicas, 2414 Microbiología, 3212 Salud Publica |
| الوصف: | Producción Científica ; Bacteremia has been associated with severity in some infections; however, its impact on the prognosis of urinary tract infections (UTIs) is still disputed. Our goal is to determine the risk factors for bacteremia and its clinical impact on hospitalized patients with complicated community-acquired urinary tract infections. We conducted a prospective observational study of patients admitted to the hospital with complicated community-acquired UTIs. Clinical variables and outcomes of patients with and without bacteremia were compared, and multivariate analysis was performed to identify risk factors for bacteremia and mortality. Of 279 patients with complicated community-acquired UTIs, 37.6% had positive blood cultures. Risk factors for bacteremia by multivariate analysis were temperature ≥ 38 °C (p = 0.006, OR 1.3 (95% CI 1.1–1.7)) and procalcitonin ≥ 0.5 ng/mL (p = 0.005, OR 8.5 (95% CI 2.2–39.4)). In-hospital and 30-day mortality were 9% and 13.6%, respectively. Quick SOFA (p = 0.030, OR 5.4 (95% CI 1.2–24.9)) and Barthel Index <40% (p = 0.020, OR 4.8 (95% CI 1.3–18.2)) were associated with 30-day mortality by multivariate analysis. However, bacteremia was not associated with 30-day mortality (p = 0.154, OR 2.7 (95% CI 0.7–10.3)). Our study found that febrile community-acquired UTIs and elevated procalcitonin were risk factors for bacteremia. The outcomes in patients with bacteremia were slightly worse, but without significant differences in mortality. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2076-2607 |
| Relation: | https://www.mdpi.com/2076-2607/11/8/1995; https://doi.org/10.3390/microorganisms11081995; Microorganisms, 2023, Vol. 11, Nº. 8, 1995; https://uvadoc.uva.es/handle/10324/67686; 1995; Microorganisms; 11 |
| DOI: | 10.3390/microorganisms11081995 |
| الاتاحة: | https://uvadoc.uva.es/handle/10324/67686 https://doi.org/10.3390/microorganisms11081995 |
| Rights: | Atribución 4.0 Internacional ; info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/ ; © 2023 The authors |
| رقم الانضمام: | edsbas.B91310D8 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20762607 |
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| DOI: | 10.3390/microorganisms11081995 |