Academic Journal
Tailoring Zinc Oxide Nanoparticles via Microwave-Assisted Hydrothermal Synthesis for Enhanced Antibacterial Properties
| العنوان: | Tailoring Zinc Oxide Nanoparticles via Microwave-Assisted Hydrothermal Synthesis for Enhanced Antibacterial Properties |
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| المؤلفون: | Irina Elena Doicin, Manuela Daniela Preda, Ionela Andreea Neacsu, Vladimir Lucian Ene, Alexandra Catalina Birca, Bogdan Stefan Vasile, Ecaterina Andronescu |
| المصدر: | Applied Sciences, Vol 14, Iss 17, p 7854 (2024) |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2024 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | zinc oxide, microwave-assisted hydrothermal method, antimicrobial activity, particle size, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999 |
| الوصف: | In recent years, significant advancements in nanotechnology have facilitated the synthesis of zinc oxide (ZnO) nanoparticles with tailored sizes and shapes, offering versatile applications across various fields, particularly in biomedicine. ZnO’s multifunctional properties, such as semiconductor behavior, luminescence, photocatalytic activity, and antibacterial efficacy, make it highly attractive for biomedical applications. This study focuses on synthesizing ZnO nanoparticles via the microwave-assisted hydrothermal method, varying the precursor concentrations (0.3488 mol/L, 0.1744 mol/L, 0.0872 mol/L, 0.0436 mol/L, and 0.0218 mol/L) and reaction times (15, 30, and 60 min). Characterization techniques, including X-ray diffraction, scanning electron microscopy, transmission electron microscopy, BET surface area analysis, and Fourier transform infrared spectroscopy were employed to assess the structural, morphological, and chemical properties. The predominant morphology is observed to be platelets, which exhibit a polygonal shape with beveled corners and occasionally include short rod-like inserts. The thickness of the platelets varies between 10 nm and 50 nm, increasing with the concentration of Zn 2+ in the precursor solution. Preliminary antimicrobial studies indicated that all strains ( S. aureus , E. coli , and C. albicans ) were sensitive to interaction with ZnO, exhibiting inhibition zone diameters greater than 10 mm, particularly for samples with lower precursor concentrations. Cell viability studies on human osteoblast cells demonstrated good compatibility, affirming the potential biomedical applicability of synthesized ZnO nanoparticles. This research underscores the influence of synthesis parameters on the properties of ZnO nanoparticles, offering insights for optimizing their design for biomedical applications. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2076-3417 |
| Relation: | https://www.mdpi.com/2076-3417/14/17/7854; https://doaj.org/toc/2076-3417; https://doaj.org/article/e5111252393e46b1b625240a5179f586 |
| DOI: | 10.3390/app14177854 |
| الاتاحة: | https://doi.org/10.3390/app14177854 https://doaj.org/article/e5111252393e46b1b625240a5179f586 |
| رقم الانضمام: | edsbas.B7FBD103 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20763417 |
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| DOI: | 10.3390/app14177854 |