Academic Journal

Solid-Phase Synthesis of Cellulose Acetate Butyrate as Microsphere Wall Materials for Sustained Release of Emamectin Benzoate

التفاصيل البيبلوغرافية
العنوان: Solid-Phase Synthesis of Cellulose Acetate Butyrate as Microsphere Wall Materials for Sustained Release of Emamectin Benzoate
المؤلفون: Aimin Huang, Xuanhai Li, Xingtang Liang, Yanjuan Zhang, Huayu Hu, Yanzhen Yin, Zuqiang Huang
المصدر: Polymers; Volume 10; Issue 12; Pages: 1381
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2018
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: cellulose acetate butyrate, solid-phase synthesis, mechanical activation, microspheres, emamectin benzoate, release
الوصف: Emamectin benzoate (EB), a widely used pesticide, is prone to decomposition by ultraviolet light and suffers from the corresponding loss of efficacy. The timed release of EB based on microspheres is one of the effective methods to solve this issue. As a non-toxic cellulose ester, cellulose acetate butyrate (CAB) is regarded as one of the best wall-forming materials for microcapsules with a good controlled release performance. Herein, two methods—mechanical activation (MA) technology and a conventional liquid phase (LP) method—were employed to synthesize different CABs, namely CAB-MA and CAB-LP, respectively. The molecular structure, rheological property, and thermal stability of these CABs were investigated. The two CABs were used to prepare microspheres for the loading and release of EB via an o/w (oil-in-water) solvent evaporation method. Moreover, the performances such as drug loading, drug entrapment, and anti-photolysis of the drug for these microspheres were studied. The results showed that both CABs were available as wall materials for loading and releasing EB. Compared with CAB-LP, CAB-MA presented a lower molecular weight and a narrower molecular weight distribution. Moreover, the MA method endowed the CAB with more ester substituent groups and less crystalline structure in comparison to the LP method, which had benefits including pelletizing and drug loading.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
Relation: Biomacromolecules, Biobased and Biodegradable Polymers; https://dx.doi.org/10.3390/polym10121381
DOI: 10.3390/polym10121381
الاتاحة: https://doi.org/10.3390/polym10121381
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.B7791CD8
قاعدة البيانات: BASE