Academic Journal
Change in visceral adiposity is an independent predictor of future arterial pulse pressure
| العنوان: | Change in visceral adiposity is an independent predictor of future arterial pulse pressure |
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| المؤلفون: | Han, SJ, Fujimoto, WY, Kahn, SE, Leonetti, DL, Boyko, EJ |
| المساهمون: | 106949, 한, 승진 |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adiposity, Adult, Arterial Pressure, Asian Americans, Body Composition, Female, Humans, Intra-Abdominal Fat, Male, Middle Aged, Organ Size, Predictive Value of Tests, Risk Factors, Subcutaneous Fat, Abdominal, Thigh, Time Factors, Vascular Stiffness, arterial pulse pressure, prospective studies, epidemiology |
| الوصف: | OBJECTIVES: Pulse pressure (PP), a marker of arterial stiffness, and body composition are both risk factors for cardiovascular disease. Little is known about whether changes in body composition may be linked to future PP. We sought to determine whether change in amount of abdominal and thigh fat over 5 years predicted PP at 10 years. METHODS: Visceral fat as well as abdominal and thigh subcutaneous fat areas were measured by computed tomography at baseline and 5 years later in 284 Japanese Americans (mean age 49.3 years: 50.4% men) without hypertension, heart disease, and glucose-lowering medication use at baseline. PP at 10 years was calculated as the difference between SBP and DBP measured with a mercury sphygmomanometer. The association between change in fat at 5 years and arterial PP at 10 years, adjusted for baseline PP, was examined using linear regression analysis. MAIN RESULTS: Change in abdominal visceral fat area at 5 years was positively associated with 10-year PP independent of sex, 5-year change in BMI, and baseline age, BMI, PP, abdominal visceral fat, smoking status, alcohol consumption, physical activity, homeostasis model assessment insulin resistance, and fasting plasma glucose. There were no significant associations between baseline amounts or change in abdominal or thigh subcutaneous fat areas and future PP. CONCLUSION: The accumulation of abdominal visceral fat over time independently predicted future PP in Japanese Americans. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0263-6352 1473-5598 |
| Relation: | J002636352; http://repository.ajou.ac.kr/handle/201003/16714; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843562/; Journal of hypertension, 36(2). : 299-305, 2018 |
| DOI: | 10.1097/HJH.0000000000001532 |
| الاتاحة: | http://repository.ajou.ac.kr/handle/201003/16714 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843562/ https://doi.org/10.1097/HJH.0000000000001532 |
| رقم الانضمام: | edsbas.B6FEA825 |
| قاعدة البيانات: | BASE |
| تدمد: | 02636352 14735598 |
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| DOI: | 10.1097/HJH.0000000000001532 |