Academic Journal
Decavanadates and polyanion-polycation interactions: from minerals to proteins
| العنوان: | Decavanadates and polyanion-polycation interactions: from minerals to proteins |
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| المؤلفون: | Hawthorne, Frank C. |
| المساهمون: | Natural Sciences and Engineering Research Council of Canada |
| المصدر: | Rendiconti Lincei. Scienze Fisiche e Naturali ; ISSN 2037-4631 1720-0776 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2024 |
| الوصف: | The decavanadate polyanions [V 10 O 28 ] 6– , [H x V 10 O 28 ] (6–x)– and [(M 4+ x V 5+ 10–x )O 28 ] (6+x)– are constituents of the pascoite-family minerals. The interaction between the interstitial complex and the decavanadate structural unit may be analyzed using the principle of correspondence of Lewis acidity-basicity. The Lewis base strengths of the decavanadate polyanions vary from 0.054 to 0.135 vu and [V 10 O 28 ] structures can form from Cs + , Rb + , K + , Tl + and Na + ; simple cations with higher Lewis acidities are too acidic to form structures. Such cations bond to transformer (H 2 O) groups to form polyatomic cations that have lower Lewis acidities than the corresponding simple cations. In the pascoite-family minerals, the stereochemical details of the decavanadate ion are modified by (1) exploiting the two different patterns of bond-length arrangement in [6] V 5+ , (2) substituting tetravalent cations for V 5+ at one of the octahedra, and (3) protonating the decavanadate ion. These mechanisms change the individual Lewis basicities of the 26 external O 2– ions of the polyanion, allowing great versatility in the binding of decavanadate ions to constituent polycations of crystallizing structures. This suggests that the [V 10 O 28 ] polyanions may be used to induce co-crystallization of large aqueous polyatomic cations, facilitating their structural characterization. Decavanadate can also induce crystallization of proteins and is of major importance in protein crystallography because of this capability. Proteins and enzymes can bind to the decavanadate ion as very large polyatomic cations, modifying their function and showing potential for treating various forms of cancer, Alzheimer’s disease, AIDS, diabetes and COVID-19. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1007/s12210-024-01290-5 |
| DOI: | 10.1007/s12210-024-01290-5.pdf |
| DOI: | 10.1007/s12210-024-01290-5/fulltext.html |
| الاتاحة: | https://doi.org/10.1007/s12210-024-01290-5 https://link.springer.com/content/pdf/10.1007/s12210-024-01290-5.pdf https://link.springer.com/article/10.1007/s12210-024-01290-5/fulltext.html |
| Rights: | https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.B6B0E60E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s12210-024-01290-5 |
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