Academic Journal
Life-History Trade-Offs in Drosophila: Flies Select a Diet to Maximize Reproduction at the Expense of Lifespan
| العنوان: | Life-History Trade-Offs in Drosophila: Flies Select a Diet to Maximize Reproduction at the Expense of Lifespan |
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| المؤلفون: | Strilbytska, Olha, Yurkevych, Ihor, Semaniuk, Uliana, Gospodaryov, Dmytro, Simpson, Stephen J, Lushchak, Oleh |
| المساهمون: | Le Couteur, David G, National Research Foundation of Ukraine |
| المصدر: | The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences ; volume 79, issue 5 ; ISSN 1079-5006 1758-535X |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2024 |
| الوصف: | Macronutrient intake impacts physiology, behavior, and gene expression in a wide range of organisms. We used the response surface methodology to compare how life history traits, lifespan, and reproduction differ as a function of protein and carbohydrate intakes under choice and no-choice feeding regimens in the fruit fly, Drosophila melanogaster. We found that when offered a choice of nutritionally complementary foods mated female flies regulated toward a protein to carbohydrate ratio (P:C) that was associated with shortened lifespan and maximal egg production when compared to response surfaces derived from flies fed 1 of a range of fixed diets differing in P:C (no-choice regimen). This difference in lifespan between choice and no-choice feeding was not seen in males or virgin flies, reflecting the fact that increased protein intake is triggered by mating to support egg production. However, whereas in mated females a higher P:C intake was associated with greater egg production under both choice and no-choice feeding, contrary to expectations, choice-fed mated flies laid fewer eggs than no-choice flies on equivalent macronutrient intakes, perhaps reflecting that they had to ingest twice the volume of food to attain an equivalent intake of nutrients than no-choice flies on a diet of equivalent P:C ratio. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1093/gerona/glae057 |
| DOI: | 10.1093/gerona/glae057/56798737/glae057.pdf |
| الاتاحة: | http://dx.doi.org/10.1093/gerona/glae057 https://academic.oup.com/biomedgerontology/advance-article-pdf/doi/10.1093/gerona/glae057/56798737/glae057.pdf https://academic.oup.com/biomedgerontology/article-pdf/79/5/glae057/57343322/glae057.pdf |
| Rights: | https://academic.oup.com/pages/standard-publication-reuse-rights |
| رقم الانضمام: | edsbas.B69AF870 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/gerona/glae057 |
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