Academic Journal
Particle Image Velocimetry to Evaluate Pulse Wave Velocity in Aorta Phantom with the lnD–U Method
| العنوان: | Particle Image Velocimetry to Evaluate Pulse Wave Velocity in Aorta Phantom with the lnD–U Method |
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| المؤلفون: | Moravia, Anaïs, Simoëns, Serge, El Hajem, Mahmoud, Bousaïd, Benyebka, Menut, Marine, Kulisa, Pascale, Lermusiaux, Patrick, Della-Schiava, Nellie |
| المساهمون: | Laboratoire de Mecanique des Fluides et d'Acoustique (LMFA), École Centrale de Lyon (ECL), Université de Lyon-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Mécanique des Contacts et des Structures Villeurbanne (LaMCoS), Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS), Hôpital Louis Pradel CHU - HCL, Hospices Civils de Lyon (HCL) |
| المصدر: | ISSN: 1869-408X. |
| بيانات النشر: | HAL CCSD Springer |
| سنة النشر: | 2022 |
| المجموعة: | HAL Lyon 1 (University Claude Bernard Lyon 1) |
| مصطلحات موضوعية: | Pulse Wave Velocity, aorta, phantom, circulatory mock loop, Particle Image Velocimetry, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph], [SPI.MECA.MEFL]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph] |
| الوصف: | International audience ; Purpose: Pulse Wave Velocity (PWV) is an indicator of arterial stiffness used in the prediction of cardiovascular disease such as atherosclerosis. Non-invasive methods performed with ultrasound probes allow one to compute PWV and aortic stiffness through the measurement of the aortic diameter (D) and blood flow velocity (U) with the lnD-U method. This technique based on in vivo acquisitions lacks validation since the aortic elasticity modulus cannot be verified with mechanical strength tests.Method: In the present study, an alternative validation is carried out on an aorta phantom hosted in an aortic flow simulator which mimics pulsatile inflow conditions. This in vitro setup included a Particle Image Velocimetry device to visualize flow in a 2D longitudinal section of the phantom, compute velocity fields (U), and track wall displacements in the aorta phantom to measure the apparent diameter (AD) variations throughout cycles.Results: The lnD-U method was then applied to evaluate PWV (5.92 ± 0.32 m/s) and calculate the Young's's modulus of the aorta phantom (0.66 ± 0.08 MPa). This last value was compared to the elasticity modulus (0.53 ± 0.07 MPa) evaluated with tensile strength tests on samples cut from the silicone phantom.Conclusion: Considering the uncertainties from the two methods, the measured elasticities are consistent and close to a 50-60 years old male aortic behavior. A comparison with in vivo data shows that the choice of silicone for the phantom material is a relevant and promising option to mimic the human aorta on in vitro systems. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | hal-03842776; https://hal.science/hal-03842776; https://hal.science/hal-03842776/document; https://hal.science/hal-03842776/file/CardiovascEngAndTec-A-Moravia2022.pdf |
| DOI: | 10.1007/s13239-022-00642-2 |
| الاتاحة: | https://hal.science/hal-03842776 https://hal.science/hal-03842776/document https://hal.science/hal-03842776/file/CardiovascEngAndTec-A-Moravia2022.pdf https://doi.org/10.1007/s13239-022-00642-2 |
| Rights: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.B5FA2EC |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s13239-022-00642-2 |
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