Academic Journal
An international cross-sectional survey of antimicrobial stewardship programmes in hospitals
| العنوان: | An international cross-sectional survey of antimicrobial stewardship programmes in hospitals |
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| المؤلفون: | Howard, P., Pulcini, C., Levy Hara, G., West, R., Gould, I., Harbarth, S., Nathwani, D. |
| المساهمون: | Leeds Teaching Hospitals NHS Trust, Maladies chroniques, santé perçue, et processus d'adaptation (APEMAC), Université Paris Descartes - Paris 5 (UPD5)-Université de Lorraine (UL), Service des Maladies Infectieuses et Tropicales CHRU Nancy, Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Hospital Carlos G. Durand, Leeds Institute for Health Sciences (LIHS), Faculty of Medicine and Health Leeds, University of Leeds-University of Leeds, Aberdeen Royal Infirmary, Prévention et contrôle des infections (PCI ), Hôpitaux Universitaires de Genève (HUG), Ninewells Hospital and Medical School Dundee |
| المصدر: | ISSN: 0305-7453. |
| بيانات النشر: | HAL CCSD Oxford University Press (OUP) |
| سنة النشر: | 2015 |
| المجموعة: | Université de Lorraine: HAL |
| مصطلحات موضوعية: | antibiotic management, antibiotic policy, antibiotic prescription, MESH: Anti-Bacterial Agents, MESH: Cross-Sectional Studies, MESH: Drug Prescriptions, MESH: Drug Utilization, MESH: Global Health, MESH: Health Services Research, MESH: Hospitals, MESH: Humans, MESH: Organizational Policy, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
| الوصف: | International audience ; OBJECTIVES:To report the extent and components of global efforts in antimicrobial stewardship (AMS) in hospitals.METHODS:An Internet-based survey comprising 43 questions was disseminated worldwide in 2012.RESULTS:Responses were received from 660 hospitals in 67 countries: Africa, 44; Asia, 50; Europe, 361; North America, 72; Oceania, 30; and South and Central America, 103. National AMS standards existed in 52% of countries, 4% were planning them and 58% had an AMS programme. The main barriers to implementing AMS programmes were perceived to be a lack of funding or personnel, a lack of information technology and prescriber opposition. In hospitals with an existing AMS programme, AMS rounds existed in 64%; 81% restricted antimicrobials (carbapenems, 74.3%; quinolones, 64%; and cephalosporins, 58%); and 85% reported antimicrobial usage, with 55% linking data to resistance rates and 49% linking data to infection rates. Only 20% had electronic prescribing for all patients. A total of 89% of programmes educated their medical, nursing and pharmacy staff on AMS. Of the hospitals, 38% had formally reviewed their AMS programme: reductions were reported by 96% of hospitals for inappropriate prescribing, 86% for broad-spectrum antibiotic use, 80% for expenditure, 71% for healthcare-acquired infections, 65% for length of stay or mortality and 58% for bacterial resistance.CONCLUSIONS:The worldwide development and implementation of AMS programmes varies considerably. Our results should inform and encourage the further evaluation of this with a view to promoting a worldwide stewardship framework. The prospective measurement of well-defined outcomes of the impact of these programmes remains a significant challenge. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/25527272; hal-01809834; https://hal.univ-lorraine.fr/hal-01809834; PUBMED: 25527272 |
| DOI: | 10.1093/jac/dku497 |
| الاتاحة: | https://hal.univ-lorraine.fr/hal-01809834 https://doi.org/10.1093/jac/dku497 |
| رقم الانضمام: | edsbas.B5C29F0A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/jac/dku497 |
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