Academic Journal
Maternal outcomes and risk factors for COVID-19 severity among pregnant women.
| العنوان: | Maternal outcomes and risk factors for COVID-19 severity among pregnant women. |
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| المؤلفون: | Vouga, M., Favre, G., Martinez-Perez, O., Pomar, L., Acebal, L.F., Abascal-Saiz, A., Hernandez, MRV, Hcini, N., Lambert, V., Carles, G., Sichitiu, J., Salomon, L., Stirnemann, J., Ville, Y., de Tejada, B.M., Goncé, A., Hawkins-Villarreal, A., Castillo, K., Solsona, E.G., Trigo, L., Cleary, B., Geary, M., Bartels, H., Al-Kharouf, F., Malone, F., Higgins, M., Keating, N., Knowles, S., Poncelet, C., Ribeiro-do-Valle, C.C., Surita, F., Dantas-Silva, A., Borrelli, C., Luz, A.G., Fuenzalida, J., Carvajal, J., Canales, M.G., Hernandez, O., Grechukhina, O., Ko, A.I., Reddy, U., Figueiredo, R., Moucho, M., Pinto, P.V., De Luca, C., De Santis, M., de Campos, D.A., Martins, I., Garabedian, C., Subtil, D., Bohrer, B., Da Rocha Oppermann, M.L., Wender, MCO, Schuler-Faccini, L., Sanseverino, MTV, Giugliani, C., Friedrich, L., Scherer, M.H., Mottet, N., Ducarme, G., Pelerin, H., Moreau, C., Breton, B., Quibel, T., Rozenberg, P., Giannoni, E., Granado, C., Monod, C., Mueller, D., Hoesli, I., Bassler, D., Heldstab, S., Kölble, N.O., Sentilhes, L., Charvet, M., Deprest, J., Richter, J., Van der Veeken, L., Eggel-Hort, B., Plantefeve, G., Derouich, M., Calvache, AJN, Lopez-Giron, M.C., Burgos-Luna, J.M., Escobar-Vidarte, M.F., Hecher, K., Tallarek, A.C., Hadar, E., Haratz, K.K., Amikam, U., Malinger, G., Maymon, R., Yogev, Y., Schäffer, L., Toussaint, A., Rossier, M.C., De Sa, RAM, Grawe, C., Aebi-Popp, K., Radan, A.P., Raio, L., Surbek, D., Böckenhoff, P., Strizek, B., Kaufmann, M., Bloch, A., Boulvain, M., Johann, S., Heldstab, S.A., Bernasconi, M.T., Grant, G., Feki, A., Brochut, A.M., Giral, M., Sedille, L., Papadia, A., Brugger, R.C., Weber, B., Fischer, T., Kahlert, C., Saines, K.N., Cambou, M., Kanellos, P., Chen, X., Yin, M., Haessig, A., Ackermann, S., Baud, D., Panchaud, A. |
| المصدر: | Scientific reports, vol. 11, no. 1, pp. 13898 |
| سنة النشر: | 2021 |
| المجموعة: | Université de Lausanne (UNIL): Serval - Serveur académique lausannois |
| مصطلحات موضوعية: | Adult, COVID-19/virology, Case-Control Studies, Female, Humans, Pregnancy, Pregnancy Complications, Infectious/virology, Pregnancy Outcome, Pregnant Women, Premature Birth/virology, Risk Factors, SARS-CoV-2/pathogenicity |
| الوصف: | Pregnant women may be at higher risk of severe complications associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which may lead to obstetrical complications. We performed a case control study comparing pregnant women with severe coronavirus disease 19 (cases) to pregnant women with a milder form (controls) enrolled in the COVI-Preg international registry cohort between March 24 and July 26, 2020. Risk factors for severity, obstetrical and immediate neonatal outcomes were assessed. A total of 926 pregnant women with a positive test for SARS-CoV-2 were included, among which 92 (9.9%) presented with severe COVID-19 disease. Risk factors for severe maternal outcomes were pulmonary comorbidities [aOR 4.3, 95% CI 1.9-9.5], hypertensive disorders [aOR 2.7, 95% CI 1.0-7.0] and diabetes [aOR2.2, 95% CI 1.1-4.5]. Pregnant women with severe maternal outcomes were at higher risk of caesarean section [70.7% (n = 53/75)], preterm delivery [62.7% (n = 32/51)] and newborns requiring admission to the neonatal intensive care unit [41.3% (n = 31/75)]. In this study, several risk factors for developing severe complications of SARS-CoV-2 infection among pregnant women were identified including pulmonary comorbidities, hypertensive disorders and diabetes. Obstetrical and neonatal outcomes appear to be influenced by the severity of maternal disease. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/34230507; info:eu-repo/semantics/altIdentifier/eissn/2045-2322; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_8A07BDF1213E8; https://serval.unil.ch/notice/serval:BIB_8A07BDF1213E; http://europepmc.org/abstract/med/34230507; https://serval.unil.ch/resource/serval:BIB_8A07BDF1213E.P001/REF.pdf |
| DOI: | 10.1038/s41598-021-92357-y |
| الاتاحة: | https://serval.unil.ch/notice/serval:BIB_8A07BDF1213E https://doi.org/10.1038/s41598-021-92357-y http://europepmc.org/abstract/med/34230507 https://serval.unil.ch/resource/serval:BIB_8A07BDF1213E.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_8A07BDF1213E8 |
| Rights: | info:eu-repo/semantics/openAccess ; CC BY 4.0 ; https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.B52BFADB |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41598-021-92357-y |
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