Academic Journal
Molecular cloning of a murine N‐type calcium channel α1 subunit ; Evidence for isoforms, brain distribution, and chromosomal localization
العنوان: | Molecular cloning of a murine N‐type calcium channel α1 subunit ; Evidence for isoforms, brain distribution, and chromosomal localization |
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المؤلفون: | Coppola, Thierry, Waldmann, Rainer, Borsotto, Marc, Heurteaux, Catherine, Romey, Georges, Mattéi, Marie-Geneviève, Lazdunski, Michel |
المصدر: | FEBS Letters ; volume 338, issue 1, page 1-5 ; ISSN 0014-5793 1873-3468 |
بيانات النشر: | Wiley |
سنة النشر: | 1994 |
المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
الوصف: | A cDNA encoding a N‐type Ca 2+ channel has been cloned from the murine neuroblastoma cell line N1A103. The open reading frame encodes a protein of 2,289 amino acids (257 kDa). Analysis of different clones provided evidence for the existence of distinct isoforms of N‐type channels. High levels of mRNA were found in the pyramidal cell layers CA1, CA2 and CA3 of the hippocampus, in the dentate gyrus, in the cortex layers 2 and 4, in the subiculum and the habenula. The N‐type Ca 2+ channel gene has been localized on the chromosome 2, band A. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
DOI: | 10.1016/0014-5793(94)80105-3 |
DOI: | 10.1016/0014-5793%2894%2980105-3 |
الاتاحة: | http://dx.doi.org/10.1016/0014-5793(94)80105-3 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793%2894%2980105-3 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793(94)80105-3 https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/0014-5793%2894%2980105-3 |
Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
رقم الانضمام: | edsbas.B4ED0CD4 |
قاعدة البيانات: | BASE |
DOI: | 10.1016/0014-5793(94)80105-3 |
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