Academic Journal
Large-scale serological survey on Mycobacterium avium subsp. paratuberculosis infection in sheep and goat herds in Sicily, Southern Italy
| العنوان: | Large-scale serological survey on Mycobacterium avium subsp. paratuberculosis infection in sheep and goat herds in Sicily, Southern Italy |
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| المؤلفون: | Di Marco Lo Presti, Vincenzo, Ippolito, Dorotea, Migliore, Sergio, Tolone, Marco, Mignacca, Sebastian Alessandro, Marino, Anna Maria Fausta, Amato, Benedetta, Calogero, Rosita, Vitale, Maria, Vicari, Domenico, Ciarello, Flavia Pruiti, Fiasconaro, Michele |
| المصدر: | Frontiers in Veterinary Science ; volume 11 ; ISSN 2297-1769 |
| بيانات النشر: | Frontiers Media SA |
| سنة النشر: | 2024 |
| المجموعة: | Frontiers (Publisher - via CrossRef) |
| الوصف: | Introduction Paratuberculosis (PTB) is a worldwide chronic, contagious enteric disease caused by Mycobacterium avium subsp. paratuberculosis (MAP) mainly affecting ruminant species. PTB is a WOAH-listed disease with direct and indirect economic losses in the livestock sector, negative impact on animal welfare and significant public health concerns. In spite of this, MAP prevalence in small ruminants is still unknown and the prevalence appears to be underestimated in many countries. The aim of this study is providing a first large-scale serological survey on MAP infection in small ruminants in Sicily, a region of Southern Italy with the 11.3 and 8.9% Italian national heritage of sheep and goats, respectively. Methods For this purpose, we analyzed a total of 48,643 animals reared in 439 flocks throughout Sicily. MAP seroprevalence was estimated both at herd-level and animal-level within breeds reared in all the nine sampled provinces. Results Our results revealed a high overall apparent prevalence at herd-level of 71.8% in sheep and 60.8% in goat farms with an animal-level prevalence of 4.5 and 5.1% in sheep and goats, respectively. Significant statistical differences were found between the provinces and within the breeds both in sheep and goats. Discussion Our study provides the first large-scale serological survey on PTB infection in small ruminants in Sicily and showed a high prevalence of disease depending to the species, breed and province. This study represents the first step to better understand the MAP epidemiology in a typical Mediterranean breeding context, suggesting the need of in-depth study on the herds risk factors, including the eventual presence of candidate genes for resistance/susceptibility to PTB in native breeds. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| DOI: | 10.3389/fvets.2024.1334036 |
| DOI: | 10.3389/fvets.2024.1334036/full |
| الاتاحة: | http://dx.doi.org/10.3389/fvets.2024.1334036 https://www.frontiersin.org/articles/10.3389/fvets.2024.1334036/full |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.B3F43BE3 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3389/fvets.2024.1334036 |
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