Academic Journal
Impact of depressive disorders on quality of life after middle ear surgery in patients with chronic otitis media
| العنوان: | Impact of depressive disorders on quality of life after middle ear surgery in patients with chronic otitis media |
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| المؤلفون: | Lailach, Susen, Langanke, Theresa, Zahnert, Thomas, Garthus-Niegel, Susan, Neudert, Marcus |
| المصدر: | http://lobid.org/resources/99370678531806441#!, 278(9):3217-3225. |
| سنة النشر: | 2020 |
| المجموعة: | Publisso (ZB MED-Publikationsportal Lebenswissenschaften) |
| مصطلحات موضوعية: | Tympanoplasty, Depressive Disorder [MeSH], Humans [MeSH], Prospective Studies [MeSH], Treatment Outcome [MeSH], Otitis Media/complications [MeSH], Ear, Middle [MeSH], Otology, Tympanoplasty [MeSH], Quality of Life [MeSH], Cholesteatoma, Chronic Disease [MeSH], Quality assessment, Otitis Media/surgery [MeSH], Middle ear reconstruction, Depressiveness |
| الوصف: | Purpose!#!The aim of this study was to determine whether preoperative depressive symptoms influence health-related quality of life (HRQOL) after middle ear surgery in patients with chronic otitis media (COM).!##!Methods!#!This prospective clinical case study was conducted at a tertiary referral center. All 102 patients who had undergone middle ear surgery for COM were assessed clinically and by audiometric testing (pure tone audiometry) in pre- and postoperative settings. Disease-specific HRQOL was assessed by the validated chronic otitis media outcome test 15 (COMOT-15) and the Zurich chronic middle ear inventory (ZCMEI-21). General HRQOL was measured using the short form 36 (SF-36). Depressive symptoms were assessed using the patient health questionnaire (PHQ-D). The Charlson comorbidity index (CCI) was used to classify comorbidities. The middle ear status was determined using the ossiculoplasty outcome parameter staging (OOPS) index.!##!Results!#!After middle ear surgery, the total COMOT-15 and ZCMEI-21 scores improved significantly (p < 0.001). General HRQOL (total SF-36 score) was unaffected by surgery (p < 0.05). Patients without elevated depressive symptoms had significantly better total scores for the COMOT-15 (p < 0.01), ZCMEI-21 (p < 0.001), and for SF-36 (p < 0.001) postoperatively. The results of the multiple regression analyses show that, after adjusting for the OOPS, CCI, and hearing improvement, preoperative depressiveness was significantly associated with worse postoperative COMOT-15 and ZCMEI-21 outcome scores (β = 0.425 and β = 0.362, p < 0.001).!##!Conclusion!#!Preoperative depressiveness was an essential predictive factor for HRQOL in patients with COM. This should be considered during patient selection to provide more suitable preoperative counseling. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | https://repository.publisso.de/resource/frl:6466272; https://doi.org/10.1007/s00405-020-06397-7; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328900/ |
| DOI: | 10.1007/s00405-020-06397-7 |
| الاتاحة: | https://repository.publisso.de/resource/frl:6466272 https://doi.org/10.1007/s00405-020-06397-7 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328900/ |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.B3216C18 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00405-020-06397-7 |
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