التفاصيل البيبلوغرافية
| العنوان: |
Cohort 1 and Cohort 2: Comparison of post-5 th (pre-CHMI) IFN-γ, IL2 and IFN-γ+IL2 responses to SPZ. |
| المؤلفون: |
Martha Sedegah (201887), Michael R. Hollingdale (8843579), Harini Ganeshan (83061), Maria Belmonte (201939), Jun Huang (127297), Arnel Belmonte (818807), Sandra Inoue (8985857), Rachel Velasco (8843570), Bradley Hickey (3546374), Nimfa Teneza-Mora (137221), Joanne Lumsden (364574), Sharina Reyes (201916), Jo Glenna Banania (8985845), Anatalio Reyes (8985848), Ivelese Guzman (8985863), Thomas L. Richie (8843582), Judith E. Epstein (8985875), Eileen Villasante (628418) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Immunology, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, dose, RAS, vaccine efficacy, malaria antigens CSP, vivo FluoroSpot assay, PfNF 54 sporozoites, Plasmodium falciparum malaria, CelTOS Background Immunization, IFN, subject, IL 2 responses, AMA, 27 weeks post-CHMI, protection, IMRAS, Trial registration ClinicalTrials.g., TRAP, radiation-attenuated Plasmodium fal., VE, Cohort 2 responses, 15 mer peptides |
| الوصف: |
Cohort 1: protected (n = 6), non-protected (n = 5); Cohort 2: protected (n = 9), non-protected (n = 1). Post-5 th (pre-CHMI) Cohort 1 and Cohort 2 IFN-γ, IL2 and IFN-γ+IL2 responses to SPZ of each subject are protected (P) or not protected (NP) to CHMI#1. Horizontal black lines separate subjects with positive (above) or negative (below) responses. Panel A: Cohort 1: numbers of protected subjects with higher activities than the highest responding non-protected subject were: IFN-γ (2/6), IL2 (4/6) and IFN-γ+IL2 (4/6). Panel B: Cohort 2: numbers of protected subjects with higher activities than the highest responding non-protected subject were: IFN-γ (6/9), IL2 (6/9) and IFN-γ+IL2 (4/9). |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/Cohort_1_and_Cohort_2_Comparison_of_post-5_sup_th_sup_pre-CHMI_IFN-_IL2_and_IFN-_IL2_responses_to_SPZ_/15832270 |
| DOI: |
10.1371/journal.pone.0256396.g003 |
| الاتاحة: |
https://doi.org/10.1371/journal.pone.0256396.g003 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.B317DF7E |
| قاعدة البيانات: |
BASE |