Academic Journal
Engineering Polymeric Nanosystems against Oral Diseases
| العنوان: | Engineering Polymeric Nanosystems against Oral Diseases |
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| المؤلفون: | Mercadante, Valeria, Scarpa, Edoardo, De Matteis, Valeria, Rizzello, Loris, Poma, Alessandro |
| المساهمون: | V. Mercadante, E. Scarpa, V. De Mattei, L. Rizzello, A. Poma |
| بيانات النشر: | MDPI |
| سنة النشر: | 2021 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | nanotechnologypolymeric nanoparticlesoral diseasesoral medicinecariesrestorative dentistryendodontologyperiodontologyoral cancerpre-clinical modelsclinical studie, Settore BIO/10 - Biochimica, Settore BIO/09 - Fisiologia, Settore BIO/11 - Biologia Molecolare |
| الوصف: | Nanotechnology and nanoparticles (NPs) are at the forefront of modern research, particularly in the case of healthcare therapeutic applications. Polymeric NPs, specifically, hold high promise for these purposes, including towards oral diseases. Careful optimisation of the production of polymeric NPs, however, is required to generate a product which can be easily translated from a laboratory environment to the actual clinical usage. Indeed, considerations such as biocompatibility, biodistribution, and biodegradability are paramount. Moreover, a pre-clinical assessment in adequate in vitro, ex vivo or in vivo model is also required. Last but not least, considerations for the scale-up are also important, together with an appropriate clinical testing pathway. This review aims to eviscerate the above topics, sourcing at examples from the recent literature to put in context the current most burdening oral diseases and the most promising polymeric NPs which would be suitable against them. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/33924289; info:eu-repo/semantics/altIdentifier/wos/WOS:000644601200001; volume:26; issue:8; firstpage:1; lastpage:35; numberofpages:35; journal:MOLECULES; http://hdl.handle.net/2434/858874; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85105204642 |
| DOI: | 10.3390/molecules26082229 |
| الاتاحة: | http://hdl.handle.net/2434/858874 https://doi.org/10.3390/molecules26082229 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.B28A83E8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/molecules26082229 |
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