Academic Journal
Relevance of 3D Cholangiography and Transient Elastography to Assess Cystic Fibrosis-Associated Liver Disease?
| العنوان: | Relevance of 3D Cholangiography and Transient Elastography to Assess Cystic Fibrosis-Associated Liver Disease? |
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| المؤلفون: | Lemaitre, C., Dominique, S., Billoud, E., Eliezer, M., Montialoux, H., Quillard, M., Riachi, G., Koning, E., Morisse-Pradier, H., Savoye, G., Savoye-Collet, C., Goria, O. |
| المساهمون: | Service d'Hépato-Gastroentérologie CHU Rouen, Hôpital Charles Nicolle Rouen, CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Service de pneumologie, oncologie thoracique et soins intensifs respiratoires Rouen, CHU Le Havre, Service de Radiologie CHU Rouen, Service de pneumologie, allergologie, mucoviscidose pédiatrique Rouen, Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU), Service d'Imagerie Médicale CHU Rouen, Equipe Quantification en Imagerie Fonctionnelle (QuantIF-LITIS), Laboratoire d'Informatique, de Traitement de l'Information et des Systèmes (LITIS), Université Le Havre Normandie (ULH), Normandie Université (NU)-Institut national des sciences appliquées Rouen Normandie (INSA Rouen Normandie), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA)-Université Le Havre Normandie (ULH), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA) |
| المصدر: | ISSN: 1198-2241 ; Canadian Respiratory Journal / Revue canadienne de pneumologie ; https://hal.science/hal-01643994 ; Canadian Respiratory Journal / Revue canadienne de pneumologie, 2016, 2016, pp.1 - 8. ⟨10.1155/2016/4592702⟩. |
| بيانات النشر: | HAL CCSD Pulsus |
| سنة النشر: | 2016 |
| المجموعة: | Normandie Université: HAL |
| مصطلحات موضوعية: | [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology |
| الوصف: | International audience ; Background. Cystic fibrosis-associated liver disease (CFLD) is a major cause of death. The objective of our retrospective study was to describe the relevance of magnetic resonance imaging (MRI) and liver stiffness measurement (LSM) for CFLD evaluation. Methods. All cystic fibrosis adult patients evaluated by MRI and LSM were included. MR signs of portal hypertension (PHT), dysmorphia, or cholangitis were collected and LSM expressed in kPa and Metavir. Results. Of 25 patients, 52% had abnormal MRI. Median LSM was 5.7 kPa (3.4-9.9). Three patients had F2 score and one had F3 score. In patients with PHT, LSM was 7.85 kPa (3.7-9.9) compared to 5 (3.4-7.5) in others, p = 0.02. In patients with abnormal liver function tests, 50% had increased LSM (≥F2), whereas 94% with normal tests had normal LSM (p = 0.04). Seven patients had abnormal MRI despite normal ultrasonography. Conclusions. MRI and LSM provide useful information on CFLD and may help to screen patients with PHT. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/27445541; hal-01643994; https://hal.science/hal-01643994; PUBMED: 27445541; PUBMEDCENTRAL: PMC4939173 |
| DOI: | 10.1155/2016/4592702 |
| الاتاحة: | https://hal.science/hal-01643994 https://doi.org/10.1155/2016/4592702 |
| رقم الانضمام: | edsbas.B28427FF |
| قاعدة البيانات: | BASE |
| DOI: | 10.1155/2016/4592702 |
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