Academic Journal

Enhancement Type at Contrast-enhanced Mammography and Association with Malignancy

التفاصيل البيبلوغرافية
العنوان: Enhancement Type at Contrast-enhanced Mammography and Association with Malignancy
المؤلفون: Kim, Geunwon, Mehta, Tejas S, Brook, Alexander, Du, Linda H, Legare, Kaila, Phillips, Jordana
المساهمون: Radiology
المصدر: Radiology ; 305 ; 2 ; 299 ; 306 ; United States
سنة النشر: 2023
المجموعة: University of Massachusetts, Medical School: eScholarship@UMMS
الوصف: At the time of publication of this article, Tejas Mehta is an Associate Professor in the Department of Radiology at UMass Chan Medical School. ; Background Despite the increasing use of contrast-enhanced mammography (CEM), there are limited data on the evaluation of findings on recombined images and the association with malignancy. Purpose To determine the rates of malignancy of enhancement findings on CEM images in the presence or absence of low-energy findings using the Breast Imaging Reporting and Data System (BI-RADS) lexicon developed for mammography and MRI. Materials and Methods All diagnostic CEM examinations performed at one academic institution between December 2015 and December 2019 had low-energy and recombined images retrospectively. Data were independently reviewed by three breast imaging radiologists with 5-25 years of experience using the BI-RADS mammography and MRI lexicon. Outcome was determined with pathologic analysis or 1-year imaging or clinical follow-up. The χ2 and Fisher exact tests were used for analysis. Results A total of 371 diagnostic CEM studies were performed in 371 women (mean age, 54 years ± 11[SD]). Sensitivity, specificity, positive predictive value (PPV), and negative predictive value of enhancement on CEM images was 95% (104 of 109 [95% CI: 90, 98]), 67% (176 of 262 [95% CI: 61, 73]), 55% (104 of 190 [95% CI: 47, 62]), and 97% (176 of 181 [95% CI: 94, 99]), respectively. Among 190 CEM studies with enhancing findings, enhancing lesions were more likely to be malignant when associated with low-energy findings (26% vs 59%, P < .001). Among enhancement types, mass enhancement composed 71% (99 of 140) of all malignancies with PPV of 63% when associated with low-energy findings. Foci, non-mass enhancement, and mass enhancement without low-energy findings had PPV of 6%, 24%, and 38%, respectively. Neither background parenchymal enhancement nor density was associated with enhancement type (P = .19 and P = .28, respectively). Conclusion Mass enhancement on recombined images using ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 1527-1315
Relation: Radiology; https://doi.org/10.1148/radiol.210966; Kim G, Mehta TS, Brook A, Du LH, Legare K, Phillips J. Enhancement Type at Contrast-enhanced Mammography and Association with Malignancy. Radiology. 2022 Nov;305(2):299-306. doi:10.1148/radiol.210966. Epub 2022 Jul 12. PMID: 35819328.; http://hdl.handle.net/20.500.14038/51583
DOI: 10.1148/radiol.210966
الاتاحة: https://doi.org/10.1148/radiol.210966
https://hdl.handle.net/20.500.14038/51583
رقم الانضمام: edsbas.B1823733
قاعدة البيانات: BASE
الوصف
تدمد:15271315
DOI:10.1148/radiol.210966