Academic Journal

Clinical Utility of Rapid On-Site Evaluation of Touch Imprint Cytology during Cryobiopsy for Peripheral Pulmonary Lesions

التفاصيل البيبلوغرافية
العنوان: Clinical Utility of Rapid On-Site Evaluation of Touch Imprint Cytology during Cryobiopsy for Peripheral Pulmonary Lesions
المؤلفون: Yutaka Muto, Keigo Uchimura, Tatsuya Imabayashi, Yuji Matsumoto, Hideaki Furuse, Takaaki Tsuchida
المصدر: Cancers; Volume 14; Issue 18; Pages: 4493
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2022
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: lung cancer, bronchoscopy, cryobiopsy, diagnosis, rapid on-site evaluation, touch imprint cytology
الوصف: Cryobiopsy enables us to obtain larger specimens than conventional forceps biopsy despite the caution regarding complications. This study aimed to evaluate the clinical utility of rapid on-site evaluation of touch imprint cytology (ROSE-TIC) during cryobiopsy of peripheral pulmonary lesions (PPLs). We retrospectively reviewed the data of consecutive patients who underwent cryobiopsy for solid PPLs between June 2020 and December 2021. ROSE-TIC was performed on the first specimen obtained via cryobiopsy and assessed using Diff-Quik staining. The results of ROSE-TIC for each patient were compared with the histological findings of the first cryobiopsy specimen. Sixty-three patients were enrolled in this study. Overall, 57 (90.5%) lesions were ≤30 mm in size and 37 (58.7%) had positive bronchus signs. The radial endobronchial ultrasound findings were located within and adjacent to the lesion in 46.0% and 54.0% of the cases, respectively. The sensitivity, specificity, and positive and negative predictive values of the ROSE results for histological findings of the corresponding specimens were 69.8%, 90.0%, 93.8%, and 58.1%, respectively. The concordance rate was 76.2%. In conclusion, ROSE-TIC, due to its high specificity and positive predictive value, may be a potential tool in deciding whether cryobiopsy sampling could be finished during bronchoscopy.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
Relation: https://dx.doi.org/10.3390/cancers14184493
DOI: 10.3390/cancers14184493
الاتاحة: https://doi.org/10.3390/cancers14184493
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.B179AFF9
قاعدة البيانات: BASE