التفاصيل البيبلوغرافية
| العنوان: |
Dichapetalins from the Twigs of Dichapetalum longipetalum with Cytotoxic Activities |
| المؤلفون: |
Bin Zhou (84959), Xin-Hua Gao (4692373), Min-Min Zhang (1576672), Hong-Chun Liu (1612945), Jian-Min Yue (746814) |
| سنة النشر: |
2022 |
| مصطلحات موضوعية: |
Biophysics, Biochemistry, Pharmacology, Ecology, Sociology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, spectroscopic data analysis, dichapetalum longipetalum <, 17 undescribed analogues, 7 , 17 , structural diversity, ray crystallography, cyclodammarane skeleton, butadiene appendage |
| الوصف: |
Continued efforts to expand the structural diversity of dichapetalins and explore further the cytotoxic structure–activity relationships have led to the isolation of 17 undescribed analogues, dichapelonins A–Q ( 1 – 17 ), and three known compounds ( 18 – 20 ) from the twigs of Dichapetalum longipetalum . Compounds 1 – 17 comprise five compound classes as classified by varied C6–C2 conjugates at the A ring of the 13,30-cyclodammarane skeleton, and their structures were determined by spectroscopic data analysis, experimental electronic circular dichroism measurements, and X-ray crystallography. Biological tests revealed compounds 1 – 7 with a phenyl-butadiene appendage to be the most potent cytotoxic compound type of those evaluated. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/journal_contribution/Dichapetalins_from_the_Twigs_of_i_Dichapetalum_longipetalum_i_with_Cytotoxic_Activities/21794330 |
| DOI: |
10.1021/acs.jnatprod.2c00971.s001 |
| الاتاحة: |
https://doi.org/10.1021/acs.jnatprod.2c00971.s001 |
| Rights: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.B16F01B5 |
| قاعدة البيانات: |
BASE |