Academic Journal

Antioxidant, Anti-photoaging, Anti-inflammatory, and Skin-barrier-protective Effects of Gleichenia japonica Extract

التفاصيل البيبلوغرافية
العنوان: Antioxidant, Anti-photoaging, Anti-inflammatory, and Skin-barrier-protective Effects of Gleichenia japonica Extract
المؤلفون: Song, Nuri, Shin, Seoyeon, Kim, Kimin, Choi, Sarang, Kim, Youngbae, Kim, Eun, Kim, Sunoh, Park, Kyungmok
المصدر: BioResources; Vol. 19 No. 3 (2024); 4181-4198 ; 1930-2126
بيانات النشر: NC State University, Dept. of Forest Biomaterials
سنة النشر: 2024
المجموعة: North Carolina State University (NCSU): Open Journal Systems
مصطلحات موضوعية: Gleichenia japonica, Ferns, Antioxidant, Anti-photoaging, Anti-inflammatory, Skin-barrier
الوصف: Ferns native to Korea, such as Davallia mariesii, Dicranopteris pedata, and Gleichenia japonica, possess antioxidant and antibacterial properties. However, their inhibitory effects on skin photoaging have not been demonstrated. Measurement and comparison of the antioxidant activity of three types of ferns revealed that the extract from G. japonica had the best effect. This study evaluates the potential of G. japonica extract as a new functional material for preventing skin damage caused by ultraviolet radiation. G. japonica extracts showed protective effects against ultraviolet B (UVB) radiation in human epidermal keratinocyte cells; the extracts inhibited intracellular reactive oxygen species production. In addition, collagen biosynthesis increased, and matrix metalloproteinase-1 activity and protein expression level decreased in human primary dermal fibroblast irradiated with UVB. The main peak (compound 1) of the extract was separated through high-performance liquid chromatography analysis and preparative liquid chromatography. Compound 1 is strongly inferred to be the main active ingredient because it showed better antioxidant activity and UVB protection effect than G. japonica extract. These results demonstrate the physiological effects of G. japonica extract and suggest its applicability as a new functional substance for preventing skin damage caused by ultraviolet radiation.
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
Relation: http://ojs.cnr.ncsu.edu/index.php/BRJ/article/view/23131/1089; http://ojs.cnr.ncsu.edu/index.php/BRJ/article/view/23131
الاتاحة: http://ojs.cnr.ncsu.edu/index.php/BRJ/article/view/23131
Rights: Copyright (c) 2024 Nuri Song, Seoyeon Shin, Kimin Kim, Sarang Choi, Youngbae Kim, Eun Kim, Sunoh Kim, Kyungmok Park
رقم الانضمام: edsbas.B0FBB11A
قاعدة البيانات: BASE