التفاصيل البيبلوغرافية
| العنوان: |
Exclusive Core-Janus Satellite Assembly Based on Au–Ag Janus Self-Aligned Distributions with Abundant Hotspots for Ultrasensitive Detection of CA19‑9 |
| المؤلفون: |
Hui-li Hao, Jian Zhu, Guo-jun Weng, Jian-jun Li, Yu-bo Guo, Jun-wu Zhao |
| سنة النشر: |
1753 |
| المجموعة: |
Smithsonian Institution: Figshare |
| مصطلحات موضوعية: |
Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, silica shell template, iu · ml, head physically immobilized, featuring two types, enhanced raman scattering, ca19 ‑ 9, 8 × 10, 7 × 10, 1 × 10, superior sers activity, stable sers signals, sers probe based, excellent sers performance, janus provided uniform, wide detection range, hierarchical assembly strategy, 4 , 3 × 10, neighboring janus, janus structure, janus satellites, janus satellite, individual janus, vertically self, ultrasensitive detection, ultrahigh sensitivity, thereby multiplying |
| الوصف: |
The development of surface-enhanced Raman scattering (SERS) probes with high sensitivity and stability is imminent to improve the accuracy of cancer diagnosis. Here, an exclusive core-Janus satellite (CJS) assembly was constructed by a hierarchical assembly strategy in which the Au–Ag Janus satellite is vertically self-aligned on the core surface. In the process, a silica shell template was ingeniously employed to asymmetrically mask the presatellites for the in situ formation of the Janus structure, and a series of Janus satellites with different morphologies were developed by regulating the encapsulated area of the presatellites. The ordered-oriented arrangement of Au–Ag Janus and unique heterojunction morphology permit CJS assemblies, featuring two types of plasmonic nanogaps, including intrananocrevices for individual Janus and internanogaps between neighboring Janus, thereby multiplying the “hotspots” compared to conventional core-monotonous satellites, which contributes to superior SERS activity. As anticipated, the enhancement factor of CJS assemblies was as high as 3.8 × 10 8 . Moreover, it is intriguing that the directional distribution and head physically immobilized by Janus provided uniform and stable SERS signals. The SERS probe based on the CJS assembly for the detection of carbohydrate antigen 19–9 resulted in an ultrahigh sensitivity with a limit of detection of 3.7 × 10 –5 IU·mL –1 , which is nearly 10 times lower than other SERS probes, and a wide detection range of 3 × 10 –5 to 1 × 10 4 IU·mL –1 . The CJS assembly with excellent SERS performance is promising to advance further development of the early diagnosis of pancreatic cancer. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/journal_contribution/Exclusive_Core-Janus_Satellite_Assembly_Based_on_Au_Ag_Janus_Self-Aligned_Distributions_with_Abundant_Hotspots_for_Ultrasensitive_Detection_of_CA19_9/25122512 |
| DOI: |
10.1021/acssensors.3c02416.s001 |
| الاتاحة: |
https://doi.org/10.1021/acssensors.3c02416.s001 |
| Rights: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.B00664B7 |
| قاعدة البيانات: |
BASE |