Academic Journal
In vitro evaluation of Haemonetics MCS+ apheresis platelet concentrates treated with photochemical pathogen inactivation following plasma volume reduction using the INTERCEPT Preparation Set
| العنوان: | In vitro evaluation of Haemonetics MCS+ apheresis platelet concentrates treated with photochemical pathogen inactivation following plasma volume reduction using the INTERCEPT Preparation Set |
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| المؤلفون: | Isola, H., Kientz, D., Aleil, B., Laeuffer, P., Weil, J., Wiesel, M.‐L., Laforêt, M., Lin, L., Mayaudon, V., Cazenave, J.‐P. |
| المصدر: | Vox Sanguinis ; volume 90, issue 2, page 128-130 ; ISSN 0042-9007 1423-0410 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2006 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Pathogen inactivation using the INTERCEPT Blood System™ requires platelet resuspension in InterSol™ and reduced plasma. Platelets in plasma collected on the Haemonetics MCS+® were processed on the INTERCEPT Preparation Set™ for plasma volume reduction and addition of InterSol. The use of the Preparation Set resulted in a mean platelet loss of 5·6 ± 3·4%. Subsequent photochemical treatment (PCT) with amotosalen and ultraviolet A light, and 7 days of storage, resulted in acceptable changes for platelet swirling, lactate, lactate dehydrogenase (LDH), platelet factor‐4 (PF4), p‐selectin, glycoprotein V (GpV), pO 2 , pCO 2 , tumour necrosis factor‐α (TNF‐α) and interleukin‐8 (IL‐8). All platelet units processed with the Preparation Set and PCT met European requirements for leucoreduction and pH values. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1111/j.1423-0410.2005.00723.x |
| الاتاحة: | http://dx.doi.org/10.1111/j.1423-0410.2005.00723.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1423-0410.2005.00723.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1423-0410.2005.00723.x |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.B002ED65 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/j.1423-0410.2005.00723.x |
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