Academic Journal
Temporal trends in the epidemiology of inflammatory bowel diseases in the public healthcare system in Brazil: A large population-based study
| العنوان: | Temporal trends in the epidemiology of inflammatory bowel diseases in the public healthcare system in Brazil: A large population-based study |
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| المؤلفون: | Abel B. Quaresma, Aderson O.M.C. Damiao, Claudio S.R. Coy, Daniela O. Magro, Adriano A.F. Hino, Douglas A. Valverde, Remo Panaccione, Stephanie B. Coward, Siew C. Ng, Gilaad G. Kaplan, Paulo G. Kotze |
| المصدر: | The Lancet Regional Health. Americas, Vol 13, Iss , Pp 100298- (2022) |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Incidence, Prevalence, Inflammatory bowel disease, Ulcerative colitis, Crohn's disease, Epidemiology, Public aspects of medicine, RA1-1270 |
| الوصف: | Summary: Background: Population-based data on epidemiology of Inflammatory Bowel Diseases (IBD) in Brazil are scarce. This study aims to define temporal trends of incidence and prevalence rates of Crohn's disease (CD) and ulcerative colitis (UC) in Brazil. Methods: All IBD patients from the public healthcare national system were included from January 2012 to December 2020. Average Annual Percent Change (AAPC) and 95% confidence intervals (CI) were calculated using log-linear regression for incidence and binomial regression for prevalence. Moran's I autocorrelation index was used to analyse clustering of cities by level of prevalence. Findings: A total of 212,026 IBD patients were included. Incidence of IBD rose from 9.4 in 2012 to 9.6 per 100,000 in 2020 (AAPC=0.8%; 95% CI -0.37, 1.99); for UC, incidence increased from 5.7 to 6.9 per 100,000 (AAPC=3.0%; 95% CI 1.51, 4.58) and for CD incidence decreased from 3.7 to 2.7 per 100,000 (AAPC=-3.2%; 95% CI -4.45, -2.02). Prevalence of IBD increased from 30.0 in 2012 to 100.1 per 100,000 in 2020 (AAPC=14.8%; CI 14.78-14.95); for UC, from 15.7 to 56.5 per 100,000 (AAPC=16.0%; CI 15.94, 16.17); for CD from 12.6 to 33.7 per 100,000 (AAPC=12.1% CI 11.95, 12.02). A south-north gradient was observed in 2020 prevalence rates of IBD [I=0.40 (p<0.0001)], CD [I=0.22 (p<0.0001)] and UC [I=0.42 (p<0.0001)]. Interpretation: Incidence of CD is decreasing whereas of UC is increasing, leading to stabilization in the incidence of IBD from 2012 to 2020 in Brazil. Prevalence of IBD has been climbing with 0.1% of Brazilians living with IBD in 2020. Funding: None. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2667-193X |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2667193X22001156; https://doaj.org/toc/2667-193X; https://doaj.org/article/a7d5e271f4e9493dbb013360e71e7f28 |
| DOI: | 10.1016/j.lana.2022.100298 |
| الاتاحة: | https://doi.org/10.1016/j.lana.2022.100298 https://doaj.org/article/a7d5e271f4e9493dbb013360e71e7f28 |
| رقم الانضمام: | edsbas.AE9B2088 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 2667193X |
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| DOI: | 10.1016/j.lana.2022.100298 |