Academic Journal
VORICONAZOLE-INDUCED HEPATOTOXICITY CONCISE UP-TO-DATE REVIEW
| العنوان: | VORICONAZOLE-INDUCED HEPATOTOXICITY CONCISE UP-TO-DATE REVIEW |
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| المؤلفون: | Ertem, Ozge, GÜMÜŞTEKİN, MUKADDES |
| سنة النشر: | 2022 |
| المجموعة: | Dokuz Eylül University: DSpace Repository |
| الوصف: | Voriconazole is a wide spectrum antifungal used primarily for invasive aspergillosis, an invasive mold infection occurs mostly in immunocompromised patients. Hepatotoxicity is the most common voriconazole-related adverse reaction that leads to treatment discontinuation. Even though reported incidence of hepatic adverse reactions during phase 2 and 3 clinical trials were less than 10%, observational studies in post marketing phase revealed much higher incidence reaching up to 69%. Therefore, the burden caused by hepatotoxicity and interruption of antifungal therapy put immunocompromised patients at serious risk. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | 5854ca3a-37ad-4047-bbf3-14c20ec54542; https://avesis.deu.edu.tr/publication/details/5854ca3a-37ad-4047-bbf3-14c20ec54542/oai |
| DOI: | 10.30621/jbachs.1051669 |
| الاتاحة: | https://doi.org/10.30621/jbachs.1051669 https://avesis.deu.edu.tr/publication/details/5854ca3a-37ad-4047-bbf3-14c20ec54542/oai |
| Rights: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.ABAB9DC |
| قاعدة البيانات: | BASE |
| DOI: | 10.30621/jbachs.1051669 |
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