Academic Journal
Time Spent with Saturation below 80% versus 90% in Patients with Obstructive Sleep Apnoea
| العنوان: | Time Spent with Saturation below 80% versus 90% in Patients with Obstructive Sleep Apnoea |
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| المؤلفون: | András Bikov, Stefan Frent, Oana Deleanu, Martina Meszaros, Mariela Romina Birza, Alina Mirela Popa, Andrei Raul Manzur, Loredana Gligor, Stefan Mihaicuta |
| المصدر: | Journal of Clinical Medicine, Vol 12, Iss 13, p 4205 (2023) |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2023 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | hypoxemia, cardiovascular risk, inflammation, burden, Medicine |
| الوصف: | Background: Nocturnal hypoxaemia measured as the percentage of total sleep time spent with saturation below 90% (TST90%) may better predict cardiovascular consequences of obstructive sleep apnoea (OSA) than the number of obstructive respiratory events measured with the apnoea–hypopnea index (AHI). Deeper hypoxaemia may potentially induce more severe pathophysiological consequences. However, the additional value of the percentage of total sleep time spent with saturation below 80% (TST80%) to TST90% is not fully explored. Methods: Comprehensive medical history was taken and fasting lipid and C-reactive protein levels were measured in 797 volunteers participating in two cohort studies in Hungary and Romania. Sleep parameters, including AHI, TST90% and TST80%, were recorded following a polysomnography (PSG, n = 598) or an inpatient cardiorespiratory polygraphy ( n = 199). The performance of TST80% to predict cardiovascular risk was compared with TST90% using linear and logistic regression analyses as well receiver operating characteristics curves. Sensitivity analyses were performed in patients who had PSG, separately. Results: Both parameters are significantly related to cardiovascular risk factors; however, TST80% did not show better predictive value for cardiovascular risk than TST90%. On the other hand, patients with more severe hypoxaemia reported more excessive daytime sleepiness. Conclusions: TST80% has limited additional clinical value compared to TST90% when evaluating cardiovascular risk in patients with OSA. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2077-0383 |
| Relation: | https://www.mdpi.com/2077-0383/12/13/4205; https://doaj.org/toc/2077-0383; https://doaj.org/article/0140c9f4840a43d89d0bd7a59af5505a |
| DOI: | 10.3390/jcm12134205 |
| الاتاحة: | https://doi.org/10.3390/jcm12134205 https://doaj.org/article/0140c9f4840a43d89d0bd7a59af5505a |
| رقم الانضمام: | edsbas.A9BD9087 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20770383 |
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| DOI: | 10.3390/jcm12134205 |