التفاصيل البيبلوغرافية
| العنوان: |
A PROSPECTIVE COMPARATIVE OBSERVATIONAL STUDY ON SAFETY, EFFICACY AND COST EFFECTIVENESS OF INSULIN AND THEIR ANALOGUES |
| المؤلفون: |
Rodrigues, Prudence Attilade, Balan, Anu, Purushothaman, Charumathi |
| المصدر: |
International Journal of Pharmacy and Pharmaceutical Sciences; Vol 10, Issue 7, 2018; 62-65 ; 0975-1491 ; 2656-0097 |
| بيانات النشر: |
Innovare Academic Sciences Pvt Ltd |
| سنة النشر: |
2018 |
| المجموعة: |
Innovare Academic Sciences: E-Journals |
| مصطلحات موضوعية: |
Type-2 diabetes mellitus, Human insulin, Insulin analogue, Glycosylated hemoglobin, Incremental cost-effectiveness ratio, Safety, efficacy, costeffectiveness, insulin, insulin analogues |
| الوصف: |
Objective: The objective of this study was to compare safety, efficacy and cost effectiveness of insulin and their analogues when compared with human insulin in patients with type-2 diabetes mellitus.Methods: A prospective observational study was carried out in a multispecialty hospital. The inpatients and outpatients from general medicine and endocrinology departments were included in our study for a period of 6 mo. The diabetic profile such as FBS, PPBS, HbA1c and body weight of the diabetic patients at the initial visit and follow up visit was documented.Results: This study showed a statistically significant reduction in HbA1c, PPBS, and FBS levels from the baseline in insulin analogue users. It was found that, insulin analogue with metformin showed statistical improvement (P<0.05) in FBS, PPBS, HbA1c as well as body weight and also found to be a cost-effective treatment according to Incremental cost-effectiveness ratio (ICER) decision matrix.Conclusion: This study concluded that type 2 diabetes patients underlined with the treatment using insulin analogue showed a better glycemic control when compared to human insulin. Metformin was the better OHA option in type-2 diabetes mellitus when compared with sulphonylureas and also metformin showed less weight gain than sulphonylureas. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf; text/html |
| اللغة: |
English |
| Relation: |
https://journals.innovareacademics.in/index.php/ijpps/article/view/21464/15000; https://journals.innovareacademics.in/index.php/ijpps/article/view/21464/14971; https://journals.innovareacademics.in/index.php/ijpps/article/view/21464 |
| الاتاحة: |
https://journals.innovareacademics.in/index.php/ijpps/article/view/21464 |
| رقم الانضمام: |
edsbas.A9B41B61 |
| قاعدة البيانات: |
BASE |