Dissertation/ Thesis
Μελέτη της χρήσης παραγώγων αίματος μετά από ενδοσκοπική χειρουργική παραρρινίων κόλπων ; The impact of submucosal PRP injection on wound healing after endoscopic sinus surgery
| العنوان: | Μελέτη της χρήσης παραγώγων αίματος μετά από ενδοσκοπική χειρουργική παραρρινίων κόλπων ; The impact of submucosal PRP injection on wound healing after endoscopic sinus surgery |
|---|---|
| المؤلفون: | Dinaki, Konstantina, Δινάκη, Κωνσταντίνα |
| بيانات النشر: | Aristotle University Of Thessaloniki (AUTH) Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ) |
| سنة النشر: | 2024 |
| المجموعة: | National Archive of PhD Theses (National Documentation Centre Greece) |
| مصطلحات موضوعية: | Ενδοσκοπική χειρουργική παραρρινίων, Πλάσμα πλούσιο σε αιμοπετάλια, Επούλωση, ESS, PRP, Wound healing, Κλινική Ιατρική, Ιατρική και Επιστήμες Υγείας, Ωτορινολαρυγγολογία, Clinical Medicine, Medical and Health Sciences, Otorhinolaryngology |
| الوصف: | Purpose: Chronic rhinosinusitis (CRS) is a prevalent chronic disease observed on a global scale. The utilization of endoscopic sinus surgery (ESS) has gained significant recognition as an effective intervention for individuals with CRS and nasal polyps who have not responded to conventional treatments. The need (or not) for revision surgery frequently relies on the promotion of optimal wound healing. The impact of platelet-rich plasma (PRP) on tissue healing has been extensively examined in various surgical fields. Methods: The present prospective study involved 30 patients suffering with nasal polyposis who underwent endoscopic sinus surgery. 15 patients were assigned to the PRP group, and 15 patients to the control group. The clinical follow-up of the patients took place at specific intervals, at weeks 1, 2, 3, 4, 8, 12 and 24 after the surgical procedure. The evaluator identified the existence of adhesions, crusting, bleeding, granulation and infection using a visual analogue scale score. The patients also completed the SNOT 22 questionnaire prior to surgery and at each post-operative visit. Results: The present study observed a lower incidence of crusting, hemorrhage and granulation in the PRP group during the early post operative period. Furthermore, a statistically significant difference was detected between the groups in those parameters. In the long term follow up no statistically significant differences were observed between the two groups. Conclusion: Based on the findings of the present investigation, it seems that platelet-rich plasma (PRP) is beneficial on wound healing during the early stages following the surgical procedure. The technique is characterized by its limited invasiveness, which contributes to its low risk profile and the achievement of clinically good outcomes. ; Σκοπός: Η χρόνια παραρρινοκολπίτιδα (ΧΠ) αποτελεί μία νόσο με μεγάλο επιπολασμό σε παγκόσμια κλίμακα. Η ενδοσκοπική χειρουργική παραρρινίων κόλπων θεωρείται θεραπεία εκλογής, όταν η νόσος δεν ανταποκρίνεται στη συντηρητική ... |
| نوع الوثيقة: | doctoral or postdoctoral thesis |
| اللغة: | Greek, Modern (1453-) |
| Relation: | http://hdl.handle.net/10442/hedi/56292 |
| DOI: | 10.12681/eadd/56292 |
| الاتاحة: | http://hdl.handle.net/10442/hedi/56292 https://doi.org/10.12681/eadd/56292 |
| رقم الانضمام: | edsbas.A91564E1 |
| قاعدة البيانات: | BASE |
| DOI: | 10.12681/eadd/56292 |
|---|