Academic Journal
Systematic analysis of the pharmacology of myoinositol and D-chiroinositola ; Систематический анализ фармакологии миоинозитола и D-хироинозитола
| العنوان: | Systematic analysis of the pharmacology of myoinositol and D-chiroinositola ; Систематический анализ фармакологии миоинозитола и D-хироинозитола |
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| المؤلفون: | T. E. Bogacheva, O. A. Gromova, I. Yu. Torshin, Т. Е. Богачева, О. А. Громова, И. Ю. Торшин |
| المصدر: | Pharmacokinetics and Pharmacodynamics; № 1 (2024); 4-13 ; Фармакокинетика и Фармакодинамика; № 1 (2024); 4-13 ; 2686-8830 ; 2587-7836 |
| بيانات النشر: | ООО «Издательство ОКИ» |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | метаболизм, D-chiro inositol, hepatoprotection, neurocytology, neuroprotection, steatohepatitis, metabolism, D-хироинозитол, гепатопротекция, нейроцитология, нейропротекция, стеатогепатит |
| الوصف: | The article presents an analysis of publications on myoinositol in order to clarify the possibilities of prescribing drugs based on it. Myoinositol is one of the endogenous human metabolites that has a significant effect on the functioning of cells and tissues of the whole body. The main function of myoinositol and its derivatives is to participate in intracellular signal transmission and ensure the functioning of such important receptors as insulin receptors, catecholamines, metabotropic receptors of various neurotransmitters, growth factors, etc. (Myoinositol is the basis for the synthesis of an important group of signaling molecules, inositol phosphates, which mediate signal transmission from growth factor receptors and neurotransmitters). Most inositol-dependent proteins with known functions are necessary for the vital functions of the cardiovascular, immune system, and connective tissue structure. Equally important is the role of myoinositol in maintaining the functioning of the central nervous system (including neurotrophic and neuroprotective roles), sugar metabolism (primarily the signaling cascade of insulin) and the functioning of the kidneys and liver. Myoinositol subsidies contribute to the prevention of folate-resistant malformations and neuroprotection of the brain under stress. ; В статье представлен анализ публикаций по миоинозитолу с целью уточнения возможностей назначения препаратов на его основе. Миоинозитол – один из эндогенных метаболитов человека, оказывающий существенное воздействие на функционирование клеток и тканей всего тела. Основной функцией миоинозитола и его производных является участие во внутриклеточной передаче сигнала и обеспечение функционирования таких важнейших рецепторов, как рецепторы инсулина, катехоламинов, метаботропные рецепторы различных нейромедиаторов, факторов роста и др. Миоинозитол – основа для синтеза важной группы сигнальных молекул, инозитолфосфатов, которые опосредуют передачу сигнала от рецепторов ростовых факторов и нейротрансмиттеров. Большинство ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Russian |
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| DOI: | 10.37489/2587-7836-2024-1-4-13 |
| الاتاحة: | https://www.pharmacokinetica.ru/jour/article/view/405 https://doi.org/10.37489/2587-7836-2024-1-4-13 |
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| رقم الانضمام: | edsbas.A8CDD5E |
| قاعدة البيانات: | BASE |
| DOI: | 10.37489/2587-7836-2024-1-4-13 |
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