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A novel and simple formula to predict liver mass in porcine experimental models

التفاصيل البيبلوغرافية
العنوان: A novel and simple formula to predict liver mass in porcine experimental models
المؤلفون: Lilia Martínez de la Maza, Verónica Prado, Amelia J. Hessheimer, Javier Muñoz, Juan Carlos García-Valdecasas, Constantino Fondevila
المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-6 (2019)
بيانات النشر: Nature Portfolio
سنة النشر: 2019
المجموعة: Directory of Open Access Journals: DOAJ Articles
مصطلحات موضوعية: Medicine, Science
الوصف: A primary limitation in hepatic surgery is leaving a remnant liver of adequate size and function. Experimental models have been designed to study processes of liver injury and regeneration in this context, yet a formula to accurately calculate liver mass in an animal model is lacking. This study aims to create a novel and simple formula to estimate the mass of the native liver in a species of pigs commonly used in experimental liver surgery protocols. Using data from 200 male weanling Landrace-Large White hybrid pigs, multiple linear regression analysis is used to generate the formula. Clinical features used as variables for the predictive model are body mass and length. The final formula for pig liver mass is as follows: Liver mass (g) = 26.34232 * Body mass (kg) – 1.270629 * Length (cm) + 163.0076; R2 = 0.7307. This formula for porcine liver mass is simple to use and may be helpful in studies using animals of similar characteristics to evaluate restoration of liver mass following major hepatectomy.
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 2045-2322
Relation: https://doi.org/10.1038/s41598-019-48781-2; https://doaj.org/toc/2045-2322; https://doaj.org/article/9cfa4f64a12640d6b37b2db46b4171a8
DOI: 10.1038/s41598-019-48781-2
الاتاحة: https://doi.org/10.1038/s41598-019-48781-2
https://doaj.org/article/9cfa4f64a12640d6b37b2db46b4171a8
رقم الانضمام: edsbas.A83D0ED5
قاعدة البيانات: BASE
الوصف
تدمد:20452322
DOI:10.1038/s41598-019-48781-2