Academic Journal
Mathematical Modeling of the Aqueous Solubility of Bioactive Substances of Environmental Interest ; Modelamiento matemático de la solubilidad acuosa de sustancias bioactivas de interes médioambiental
| العنوان: | Mathematical Modeling of the Aqueous Solubility of Bioactive Substances of Environmental Interest ; Modelamiento matemático de la solubilidad acuosa de sustancias bioactivas de interes médioambiental |
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| المؤلفون: | Delgado, Daniel Ricardo, Cárdenas Torres, Rossember Edén, Ortiz, Claudia Patricia |
| المساهمون: | Grupo de Investigación de Ingenierías UCC-Neiva |
| المصدر: | https://ieeexplore.ieee.org/document/10040875. |
| بيانات النشر: | Universidad Cooperativa de Colombia, Facultad de Ingenierías, Ingeniería Civil, Neiva Panama |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Apelblat, Buchowski Ksiazczak, Drugs, mathematical models, NRTL, solubility, van't Hoff Yaws, Wilson model |
| الوصف: | Solubility is one of the most important physicochemical properties of a drug, since it is the basis for any technological development, as well as one of the most important information when carrying out environmental evaluations. In this work, the Apelblat, Buchowski-Ksiazczak, van't Hoff-Yaws, NRTL and Wilson models were evaluated in the prediction of the solubility of three drugs of environmental interest because they are considered hazardous xenobiotics for the environment by the Norman network. According to the evaluation of the quality of the adjustment by calculating the mean absolute percentage error(MAPE), it was established that all the models allow calculating the solubility of the three bioactive substances with very low error percentages, i.e. Apelblat 2.98%, van't Hoff-Yaws 2.97%, Buchowski-Ksiazczak 3.35%, NRTL 7.37% and Wilson is 10.88%, which indicates that the models can be an important tool for optimizing processes involving the solubility of these drugs. ; Universidad Cooperativa de Colombia ; Energias, agua y medio ambiente |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | pdf; application/pdf |
| اللغة: | English |
| ردمك: | 978-1-66549-843-2 1-66549-843-9 |
| Relation: | N/A; 503; 498; IEEE Xplore; A. N. Martin, and P. J. Sinko, Martin's Physical Pharmacy and Pharmaceutical Sciences: Physical Chemical and Biopharmaceutical Principles in the Pharmaceutical Sciences, 6ta ed., Lippincott Williams & Wilkins, 2011, Philadelphia, 2011, pp 300-318.; J. Harrower, M. McNaughtan, C. Hunter, R. Hough, Z. Zhang, and K Helwig. “Chemical Fate and Partitioning Behavior of Antibiotics in the Aquatic Environment-A Review”, Environ. Toxicol. Chem. Vol 40, 3275–3298, 2021; J. J. Agredo-Collazos, C. P. Ortiz, N. Enrique Cerquera, R. E. Cardenas-Torres, D. R. Delgado, M. A. Peña, F. Martínez, “Equilibrium Solubility of Triclocarban in (Cyclohexane+ 1, 4-Dioxane) Mixtures: Determination, Correlation, Thermodynamics and Preferential Solvation”, J. Solut. Chem. (2022). https://doi.org/10.1007/s10953-022-01209-4.; R. E. Cárdenas-Torres, C. P. Ortiz, W. E. Acree Jr, A. Jouyban, F. Martínez, D. R. Delgado, “Thermodynamic study and preferential solvation of sulfamerazine in acetonitrile+ methanol cosolvent mixtures at different temperatures”, J. Mol. Liq. vol. 349, pp. 118172, 2022.; D. R. Delgado, R. E. Cardenas-Torres and C. P. Ortiz, "Mathematical Modeling of the Aqueous Solubility of Bioactive Substances of Environmental Interest," 2022 8th International Engineering, Sciences and Technology Conference (IESTEC), Panama, Panama, 2022, pp. 498-503, doi:10.1109/IESTEC54539.2022.00084.; https://hdl.handle.net/20.500.12494/55397 |
| الاتاحة: | https://hdl.handle.net/20.500.12494/55397 |
| Rights: | http://creativecommons.org/licenses/by-nc-nd/4.0/ ; info:eu-repo/semantics/closedAccess ; Attribution-NonCommercial-NoDerivatives 4.0 International ; http://purl.org/coar/access_right/c_14cb |
| رقم الانضمام: | edsbas.A81299DA |
| قاعدة البيانات: | BASE |
| ردمك: | 9781665498432 1665498439 |
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