Occurrence and spread of human- induced antimicrobial resistance in a large river water system: developing a holistic picture based on the Joint Danube Survey 4 activities

التفاصيل البيبلوغرافية
العنوان: Occurrence and spread of human- induced antimicrobial resistance in a large river water system: developing a holistic picture based on the Joint Danube Survey 4 activities
المؤلفون: Kirschner, Alexander K.T., Kittinger, Clemens, Schachner, Iris, Jakwerth, Stefan, Koller, Michael, Kolarević, Stoimir, Kračun-Kolarević, Margareta, Toumi, Marwene, Farkas, Rosza, Tóth, Erika, Kandler, W, Sulyok, M, Savio, Domenico, Farnleitner, Andreas H., Zarfel, Gernot
المساهمون: Sandu, Cristina, Cyffka, Bernd
المصدر: 43rd IAD Conference: Rivers and Floodplains in the Antropocene: Upcoming Challenges in the Danube River Basin
بيانات النشر: Aueninstitut Neuburg
سنة النشر: 2021
المجموعة: RADaR - Digital Repository of Archived Publications Institute for Biological Research "Sinisa Stankovic" / РАДаР - Репозиторијум Архивираних Дигиталних Радова Институт за биолошка истраживања "Синиша Станковић"
الوصف: The problem of human-induced antimicrobial resistance (acquired due to human activities) is an emerging concern in aquatic environments. The isolation of (facultative) pathogenic organisms with acquired antibiotic resistance, even concerning last-line antibiotics, from rivers and lakes, is well documented throughout the world. In the last few years, there has been a rapid increase in the number of studies addressing these topics and their possible implications for human health. However, most studies concentrate on a relatively limited methodology, e.g. applying non-quantitative and either cultivation-based or direct-detection based molecular biological methods. In addition, often only small geographic areas and short periods of time are covered. This is one of the reasons why many relevant questions concerning the occurrence and spread of antimicrobial resistance in aquatic ecosystems still remain unanswered. The largest European river water survey (Joint Danube Survey 4) offered a unique opportunity to study the occurrence and spread of human-induced antimicrobial resistance along the whole Danube River. Within the research project, isolates from samples from the entire course of the Danube and their main tributaries, including high frequency sampling at selected locations, have been collected and analysed. Samples from the water compartment but also from submerged biofilms have been considered. State-of-the-art quantitative molecular biological techniques and culture-based analyses targeting different bacterial organisms have been combined with a large set of physical, chemical and biological parameters to obtain a robust and comprehensive picture of the occurrence and spread of human-induced antimicrobial resistance in the Danube River. Based on the findings of this quantitative, integrative study approach, it seems likely to significantly improve the current understanding on the importance on the spread and stabilization of human - induced antibiotic resistance in large rivers. The results of this study will ...
نوع الوثيقة: conference object
اللغة: English
Relation: http://radar.ibiss.bg.ac.rs/handle/123456789/4731; https://radar.ibiss.bg.ac.rs/bitstream/id/9746/43rd_IAD_Conference_Proceedings-20.pdf; https://hdl.handle.net/21.15107/rcub_ibiss_4731
الاتاحة: http://radar.ibiss.bg.ac.rs/handle/123456789/4731
https://radar.ibiss.bg.ac.rs/bitstream/id/9746/43rd_IAD_Conference_Proceedings-20.pdf
https://hdl.handle.net/21.15107/rcub_ibiss_4731
Rights: openAccess ; ARR ; © 2021 by the Aueninstitut Neuburg
رقم الانضمام: edsbas.A803CBC6
قاعدة البيانات: BASE