Academic Journal
Long-lasting symptoms after an acute COVID-19 infection and factors associated with their resolution
| العنوان: | Long-lasting symptoms after an acute COVID-19 infection and factors associated with their resolution |
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| المؤلفون: | Robineau, Olivier, Zins, Marie, Touvier, Mathilde, Wiernik, Emmanuel, Lemogne, Cedric, de Lamballerie, Xavier, Blanché, Hélène, Deleuze, Jean-François, Saba Villarroel, Paola Mariela, Dorival, Céline, Nicol, Jerome, Gomes-Rima, Roselyn, Correia, Emmanuelle, Coeuret-Pellicer, Mireille, Druesne-Pecollo, Nathalie, Esseddik, Younes, Ribet, Céline, Goldberg, Marcel, Severi, Gianluca, Carrat, Fabrice |
| المساهمون: | Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Santé Publique : épidémiologie et qualité des soins (EA 2694), Faculté de Médecine Henri Warembourg - Université de Lille-Centre d'Etudes et de Recherche en Informatique Médicale Lille (CERIM), Centre Hospitalier Tourcoing, Cohortes épidémiologiques en population (CONSTANCES), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université Paris Cité (UPCité), Nutritional Epidemiology Research Team, Université Sorbonne Paris Nord-Centre for Research in Epidemiology and Statistics, Conservatoire National des Arts et Métiers CNAM (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers CNAM (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Unité des Virus Emergents (UVE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille), Fondation Jean Dausset - Centre d’Etudes du Polymorphisme Humain Paris (CEPH), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Università degli Studi di Firenze = University of Florence = Université de Florence (UniFI), CHU Saint-Antoine AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Fondation pour la Recherche Médicale: grant 20RR052-00, Institut National de la Santé et de la Recherche Médicale (INSERM) : grant C20-26, Santé, Pratiques, Relations et Inégalités Sociales en Population Générale Pendant la Crise COVID-19–Sérologie (SAPRIS-SERO) Study Group: Fabrice Carrat, Marie Zins, Gianluca Severi, Mathilde Touvier, Hélène Blanché, Jean-François Deleuze, Xavier De Lambalerie, Clovis Lusivika-Nzinga, Gregory Pannetier, Nathanael Lapidus, Isabelle Goderel, Céline Dorival, Jerome Nicol, Olviier Robineau, Sofiane Kab, Adeline Renuy, Stéphane Le-Got, Céline Ribet, Miereille Pellicer, Emmanuel Wiernik, Marcel Goldberg, Fanny Artaud, Pascale Gerbouin-Rérolle, Mélodie Nguix, Camille Laplanche, Roselyn Gomes-Rima, Lyan Hoang, Emmanuelle Correia, Alpha Amadou Barry, Nadège Senina, Julien Allegre, Fabien Szabo de Edelenyi, Nathalie Druesne-Pecollo, Yunes Esseddik, Serge Hercberg, Mélanie Deschasaux, Jean-Marc Sébaoun, Jean-Christophe Baudouin, Laetitia Gressin, Valérie Morel, Ouissam Ouili, Laetitia Ninove, Stéphane Priet, Paola Mariela Saba Villarroel, Toscane Fourié, Souand Mohamed Ali, Abdenour Amroun, Morgan Seston, Nazli Ayhan, Boris Pastorino, ANR-20-COVI-0009,SAPRIS,Santé, perception, pratiques, relations et inégalités sociales en population générale pendant la crise COVID-19(2020), ANR-10-COHO-0006,E4N,Etude Epidémiologique des Enfants de femmes de l'Education Nationale(2010) |
| المصدر: | EISSN: 2574-3805 ; JAMA Network Open ; https://hal.science/hal-03869367 ; JAMA Network Open, 2022, 5 (11), pp.e2240985. ⟨10.1001/jamanetworkopen.2022.40985⟩ ; https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2798224 |
| بيانات النشر: | HAL CCSD American Medical Association |
| سنة النشر: | 2022 |
| المجموعة: | Université de Versailles Saint-Quentin-en-Yvelines: HAL-UVSQ |
| مصطلحات موضوعية: | [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
| الوصف: | International audience ; IMPORTANCE Persistent symptoms after SARS-CoV-2 infection are an emerging public health problem. The duration of these symptoms remains poorly documented. OBJECTIVE To describe the temporal dynamics of persistent symptoms after SARS-CoV-2 infection and the factors associated with their resolution.DESIGN, SETTING, AND PARTICIPANTS This cross-sectional study involved 53 047 participants from 3 French adult population-based cohorts (CONSTANCES [Consultants des Centres d’Examens de Santé], E3N/E4N, and Nutrinet-Santé) who were included in a nationwide survey about SARSCoV-2 infection. All participants were asked to complete self-administered questionnaires between April 1 and June 30, 2020. Variables included sociodemographic characteristics, comorbid conditions, COVID-19 diagnosis, and acute symptoms. Blood samples were obtained for serologic analysis between May 1 and November 30, 2020, from patients with SARS-CoV-2 infection defined as enzyme-linked immunosorbent assay immunoglobulin G antispike detection confirmed with a neutralization assay. A follow-up internet questionnaire was completed between June 1 and September 30, 2021, with details on persistent symptoms, their duration, and SARS-CoV-2 infection diagnosis by polymerase chain reaction.MAIN OUTCOMES AND MEASURES Persistent symptoms were defined as symptoms occurring during the acute infection and lasting 2 or more months. Survival models for interval-censored data were used to estimate symptom duration from the acute episode. Multivariable adjusted hazardratios (HRs) were estimated for age, sex, and comorbid conditions. Factors associated with the resolution of symptoms were assessed.RESULTS A total of 3972 participants (2531 women [63.7%; 95% CI, 62.2%-65.2%]; mean [SD] age, 50.9 [12.7] years) had been infected with SARS-CoV-2. Of these 3972 participants, 2647 (66.6% [95% CI, 65.1%-68.1%]) reported at least 1 symptom during the acute phase. Of these 2647participants, 861 (32.5% [95% CI, 30.8%-34.3%]) reported at least 1 ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/36350653; PUBMED: 36350653; PUBMEDCENTRAL: PMC9647489 |
| DOI: | 10.1001/jamanetworkopen.2022.40985 |
| الاتاحة: | https://hal.science/hal-03869367 https://hal.science/hal-03869367v1/document https://hal.science/hal-03869367v1/file/RoZiToLEct.pdf https://doi.org/10.1001/jamanetworkopen.2022.40985 |
| Rights: | http://creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.A70741AF |
| قاعدة البيانات: | BASE |
| DOI: | 10.1001/jamanetworkopen.2022.40985 |
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