Academic Journal
Killian Jamieson Diverticulum, the Great Mimicker: A Case Series and Contemporary Review
| العنوان: | Killian Jamieson Diverticulum, the Great Mimicker: A Case Series and Contemporary Review |
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| المؤلفون: | Howell, Rebecca, Tang, Alice, Allen, Jacqui, Altaye, Mekibib, Amin, Milan, Bayan, Semirra, Belafsky, Peter, Cervenka, Brian, deSilva, Brad, Dion, Greg, Ekbom, Dale, Friedman, Aaron, Fritz, Mark, Giliberto, John Paul, Guardiani, Elizabeth, Harmon, Jeffrey, Kasperbauer, Jan L., Khosla, Sid, Kim, Brandon, Kuhn, Maggie, Kwak, Paul, Ma, Yue, Madden, Lyndsay, Matrka, Laura, Mayerhoff, Ross, Piraka, Cyrus, Rosen, Clark, Tabangin, Meredith E., Wahab, Shaun A., Wilson, Keith, Wright, S. Carter, Young, Vyvy, Yuen, Sonia, Postma, Gregory N. |
| المساهمون: | American Laryngological, Rhinological and Otological Society |
| المصدر: | The Laryngoscope ; volume 133, issue 9, page 2110-2115 ; ISSN 0023-852X 1531-4995 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2022 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Objective To assess barium esophagram (BAS) as a diagnostic marker for patients with Killian Jamieson diverticula (KJD). Methods Prospective, multicenter cohort study of individuals enrolled in the Prospective OUtcomes of Cricopharyngeus Hypertonicity (POUCH) Collaborative. Patient demographics, comorbidities, radiographic imaging reports, laryngoscopy findings, patient‐reported outcome measures (PROM), and operative reporting were abstracted from a REDCap database and summarized using means, medians, percentages, frequencies. Paired t‐tests and Wilcoxon Signed Rank test were used to test pre‐ to post‐operative differences in RSI, EAT‐10, and VHI‐10 scores. Diagnostic test evaluation including sensitivity, specificity, positive, and negative predictive value with 95% confidence intervals were calculated comparing BAS findings to operative report. Results A total of 287 persons were enrolled; 13 (4%) patients were identified with confirmed KJD on operative reports. 100% underwent open transcervical excision. BAS has a 46.2% (95% confidence interval [CI]: 23.2, 70.9) sensitivity and 97.8% (95% CI: 95.3, 99.0) specificity in detecting a KJD and 50% (95% CI: 25.4, 74.6) positive predictive value but 97.4% (95%CI: 94.8, 98.7) negative predictive value. Preoperatively, patients reported mean (SD) RSI and EAT‐10 of 19.4 (9) and 8.3 (7.5) accordingly. Postoperatively, patients reported mean (SD) RSI and EAT‐10 as 5.4 (6.2) and 2.3 (3.3). Both changes in RSI and EAT‐10 were statistically significant ( p = 0.008, p = 0.03). Conclusion KJD are rare and represent <5% of hypopharyngeal diverticula undergoing surgical intervention. Open transcervical surgery significantly improves symptoms of dysphagia. BAS has high specificity but low sensitivity in detecting KJD. Level of Evidence 4 Laryngoscope , 133:2110–2115, 2023 |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/lary.30508 |
| الاتاحة: | http://dx.doi.org/10.1002/lary.30508 https://onlinelibrary.wiley.com/doi/pdf/10.1002/lary.30508 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/lary.30508 |
| Rights: | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| رقم الانضمام: | edsbas.A61D5A24 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/lary.30508 |
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