Academic Journal
Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles
| العنوان: | Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles |
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| المؤلفون: | International Headache Genetics Consortium, HUNT All-in Headache, Danish Blood Donor Study Genomic Cohort |
| المساهمون: | Faculty of Medicine, Other departments |
| سنة النشر: | 2022 |
| المجموعة: | Opin vísindi (Iceland) |
| مصطلحات موضوعية: | Genarannsóknir, Taugasjúkdómafræði, Mígreni, Gen, Krabbameinslæknisfræði, Migraine Disorders, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Migraine Disorders/genetics, Molecular Sequence Annotation, Genetic Loci, Case-Control Studies, Central Nervous System/metabolism, Migraine with Aura/genetics, Alleles, Polymorphism, Single Nucleotide, Cardiovascular System/metabolism, Quantitative Trait Loci, Genetics |
| الوصف: | Funding Information: We thank the study participants for their contribution to this research. We also thank the numerous individuals who contributed to sample collection, storage, handling, phenotyping and genotyping for each of the individual cohorts. We acknowledge the participants and investigators of the FinnGen study. This research has been conducted using the UK Biobank Resource under Application Number 22627. We are supported by following grants: the US National Institute of Neurological Disorders and Stroke (NINDS) of the US National Institutes of Health (NIH) (grant numbers R21NS09296 and R21NS104398 (D.I.C.)), the Finnish innovation fund Sitra and Finska L?kares?llskapet (E.W.), the Academy of Finland (grant nos. 288509, 312076, 336825 (M.P.)), the Sigrid Juselius Foundation (M.P. and S.R.), the Academy of Finland Center of Excellence in Complex Disease Genetics (grant no. 312062 (S.R.)), the Finnish Foundation for Cardiovascular Research (S.R.), University of Helsinki HiLIFE Fellow and Grand Challenge grants (S.R.), The Novo Nordisk Foundation (NNF14CC0001 and NNF17OC0027594 (T.F.H. and K.B.)), CANDY foundation (CEHEAD) (T.F.H.), and the South-Eastern Norway Regional Health Authority (grant no. 2020034 (B.S.W.)). A list of study-specific acknowledgements and funding information can be found in the Supplementary Note. Funding Information: We thank the study participants for their contribution to this research. We also thank the numerous individuals who contributed to sample collection, storage, handling, phenotyping and genotyping for each of the individual cohorts. We acknowledge the participants and investigators of the FinnGen study. This research has been conducted using the UK Biobank Resource under Application Number 22627. We are supported by following grants: the US National Institute of Neurological Disorders and Stroke (NINDS) of the US National Institutes of Health (NIH) (grant numbers R21NS09296 and R21NS104398 (D.I.C.)), the Finnish innovation fund Sitra and Finska Läkaresällskapet (E.W.), ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 152-160 |
| اللغة: | English |
| تدمد: | 1061-4036 |
| Relation: | Nature Genetics; 54(2); http://www.scopus.com/inward/record.url?scp=85124577579&partnerID=8YFLogxK; International Headache Genetics Consortium , HUNT All-in Headache & Danish Blood Donor Study Genomic Cohort 2022 , ' Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles ' , Nature Genetics , vol. 54 , no. 2 , pp. 152-160 . https://doi.org/10.1038/s41588-021-00990-0; 422bc099-92e0-4953-8829-d0416008242e; 85124577579; unpaywall: 10.1038/s41588-021-00990-0; https://hdl.handle.net/20.500.11815/3029 |
| DOI: | 10.1038/s41588-021-00990-0 |
| الاتاحة: | https://hdl.handle.net/20.500.11815/3029 https://doi.org/10.1038/s41588-021-00990-0 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.A5FC1330 |
| قاعدة البيانات: | BASE |
| تدمد: | 10614036 |
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| DOI: | 10.1038/s41588-021-00990-0 |