Academic Journal
The plasma alpha-synuclein levels in patients with Parkinson�셲 disease and multiple system atrophy
| العنوان: | The plasma alpha-synuclein levels in patients with Parkinson�셲 disease and multiple system atrophy |
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| المساهمون: | P. H. Lee, G. Lee, H. J. Park, O. Y. Bang, I. S. Joo, K. Huh, Lee, Phil Hyu |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | Adult, Enzyme-Linked Immunosorbent Assay, Female, Humans, Male, Middle Aged, Multiple System Atrophy/blood, Parkinson Disease/blood, alpha-Synuclein/blood, 慣-Synuclein, Parkinson�셲 disease, multiple system atrophy |
| الوصف: | 慣-Synuclein, a synaptic protein of unknown function, is a major component of Lewy bodies and may play a role in the pathophysiological process of Parkinson�셲 disease (PD). In this study, we measured the plasma 慣-synuclein levels in 105 patients with PD, 38 patients with multiple system atrophy (MSA), and 51 age-matched controls. The 慣-synuclein level was significantly elevated in patients with PD (79.9 짹 4.0�뎟g/ml, p < 0.001) and in those with MSA (78.1 짹 3.5�뎟g/ml, p = 0.019) compared with the level in controls (76.1 짹 3.9�뎟g/ml). The 慣-synuclein level was higher in patients with PD than in those with MSA (79.9 짹 4.0 vs 78.1 짹 3.5, p = 0.016). Our study demonstrated that the 慣-synuclein level in plasma is elevated in patients with PD and MSA. ; open |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 1435~1439 |
| اللغة: | unknown |
| تدمد: | 0300-9564 1435-1463 16465458 |
| Relation: | JOURNAL OF NEURAL TRANSMISSION; J01619; OAK-2006-02071; https://ir.ymlib.yonsei.ac.kr/handle/22282913/110811; http://link.springer.com/article/10.1007%2Fs00702-005-0427-9; T200602984; JOURNAL OF NEURAL TRANSMISSION, Vol.113(10) : 1435-1439, 2006 |
| DOI: | 10.1007/s00702-005-0427-9 |
| الاتاحة: | https://ir.ymlib.yonsei.ac.kr/handle/22282913/110811 https://doi.org/10.1007/s00702-005-0427-9 http://link.springer.com/article/10.1007%2Fs00702-005-0427-9 |
| Rights: | CC BY-NC-ND 2.0 KR ; https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ ; not free |
| رقم الانضمام: | edsbas.A5FA54F7 |
| قاعدة البيانات: | BASE |
| تدمد: | 03009564 14351463 16465458 |
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| DOI: | 10.1007/s00702-005-0427-9 |