Academic Journal

Peculiar Aspects in Influence of α 1 -Adrenoceptor Stimulation on Isolated Rat Heart

التفاصيل البيبلوغرافية
العنوان: Peculiar Aspects in Influence of α 1 -Adrenoceptor Stimulation on Isolated Rat Heart
المؤلفون: Zefirov T., Khabibrakhmanov I., Ziyatdinova N., Zefirov A.
المصدر: SCOPUS00074888-2016-SID84996562231
سنة النشر: 2016
المجموعة: NORA (National aggregator of open repositories of Russian universities) / Национальный агрегатор открытых репозиториев российских университетов
الوصف: © 2016 Springer Science+Business Media New YorkThe study examined the effect of α1-adrenoceptor stimulation with methoxamine on chronotropic function of isolated heart perfused ex vivo according to Langendorff and cardiac chronotropy in vivo. Stimulation of α1-adrenoceptors in isolated heart induced gradually developing bradycardia, which progressed during several minutes. Similar stimulation in vivo produced a short-term bradycardia probably terminated by the compensatory influences in the whole organism. Comparison of the data obtained in both experimental paradigms during α1-adrenoceptor stimulation revealed unidirectional changes in cardiac chronotropy characterized with time-related peculiarities.
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
تدمد: 0007-4888
Relation: Bulletin of Experimental Biology and Medicine; http://rour.neicon.ru:80/xmlui/bitstream/rour/182454/1/nora.pdf; https://openrepository.ru/article?id=182454
الاتاحة: https://openrepository.ru/article?id=182454
رقم الانضمام: edsbas.A4B9C22
قاعدة البيانات: BASE