التفاصيل البيبلوغرافية
| العنوان: |
Prevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parameters ; Revista da Sociedade Brasileira de Medicina Tropical |
| المؤلفون: |
Paraná, Raymundo, Reis, Galvão dos, Silva, Luciano Kalabric, Silva, Maria Betânia Souza da, Lopes, Gisele Barreto, Rodart, Itatiana Ferreira, Costa, Fernando Quadros, Santana, Nelma Pereira de, Santana, Aurelino |
| المصدر: |
http://dx.doi.org/10.1590/S0037-86822005000600010. |
| بيانات النشر: |
Brasil |
| سنة النشر: |
2005 |
| مصطلحات موضوعية: |
Hepatitis C virus, Hemophilia, Prevalence, Genotype, Bahia |
| الوصف: |
p.496-502 ; The objective of the present study was to analyze HCV serological and virological parameters from hemophiliacs in the State of Bahia. Anti-HCV was investigated by ELISA in a cohort of 268 hemophiliacs A/B who were followed-up in a reference unit for hemotherapy in the State of Bahia. HCV viremia and genotypes were also determined from a subset of 66 anti-HCV seropositive hemophiliacs. Seroprevalence among hemophiliacs was 42.2% (95% CI 36.5-48.1) and was significantly higher (p<0.05) according to age >10 years, presence of factor VIII/IX inhibitory antibodies and other infection markers. None of the hemophiliacs less than 5 years of age were anti-HCV seropositive. Viremia was detectable in 77.3% (51/66). HCV genotype 1 (74%) was the most prevalent followed by genotype 3 (22%) and genotype 2 (4%). Our results indicate that HCV prevalence is still high among hemophiliacs, although HCV transmission was not observed in young hemophiliacs. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
http://repositorio.ufba.br/ri/handle/ri/13490; v.38 n. 6 |
| الاتاحة: |
http://repositorio.ufba.br/ri/handle/ri/13490 |
| Rights: |
Acesso Aberto |
| رقم الانضمام: |
edsbas.A48E3728 |
| قاعدة البيانات: |
BASE |