Academic Journal
Frystyk J: Fasting unmasks a strong inverse association between ghrelin and cortisol in serum: studies in obese and normal-weight subjects. J Clin Endocrinol Metab 90:741–746
| العنوان: | Frystyk J: Fasting unmasks a strong inverse association between ghrelin and cortisol in serum: studies in obese and normal-weight subjects. J Clin Endocrinol Metab 90:741–746 |
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| المؤلفون: | Ulrick Espelund, Troels Krarup Hansen, Kurt Højlund, Henning Beck-nielsen, Jes Thorn Clausen, Birgit Sehested Hansen, Hans Ørskov, Jens Otto, Lunde Jørgensen, Jan Frystyk |
| المساهمون: | The Pennsylvania State University CiteSeerX Archives |
| المصدر: | http://jcem.endojournals.org/content/90/2/741.full.pdf. |
| سنة النشر: | 2005 |
| المجموعة: | CiteSeerX |
| الوصف: | Administration of ghrelin, the endogenous ligand for the GH secretagogue receptor, stimulates not only GH secretion but also appetite and food intake in humans. Endogenous ghrelin levels display a distinct circadian rhythm, which is reciprocal to that of insulin and presumed to be meal dependent and not associated with GH secretion. We tested the hypothesis that food deprivation could impact circadian serum ghrelin levels and unmask meal-independent regulatory mechanisms. Thirty-three young adults, subdivided according to gender and level of obesity, were studied with blood sampling every 3 h from 12–84 h of fasting. Serum ghrelin levels showed a marked diurnal rhythm with a nadir in the morning (0800 h), peak levels in the afternoon, and a gradual decline during the night. This pattern was preserved during the entire fasting GHRELIN IS AN acylated peptide of 28 amino acids |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.325.5301; http://jcem.endojournals.org/content/90/2/741.full.pdf |
| الاتاحة: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.325.5301 http://jcem.endojournals.org/content/90/2/741.full.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: | edsbas.A4061162 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |